46340
Fisetin
≥99.0% (HPLC)
Synonym(s):
3,3′,4′,7-Tetrahydroxyflavone, 5-Deoxyquercetin, Natural Brown 1
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About This Item
Empirical Formula (Hill Notation):
C15H10O6 · xH2O
CAS Number:
Molecular Weight:
286.24 (anhydrous basis)
EC Number:
208-434-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
292829
MDL number:
InChI key
GYHFUROKCOMWNQ-UHFFFAOYSA-N
InChI
1S/C15H10O6.H2O/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7;/h1-6,16-18,20H;1H2
SMILES string
O.Oc1ccc2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
assay
≥99.0% (HPLC)
mp
>330 °C (lit.)
Gene Information
human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), GSK3A(2931)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Regulatory Information
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Sherin Jacob et al.
Biological trace element research, 177(2), 297-315 (2016-11-07)
Methyl mercury (MeHg) is a developmental neurotoxin that causes irreversible cognitive damage in offspring of gestationally exposed mothers. Currently, no preventive drugs are established against MeHg developmental neurotoxicity. The neuroprotective effect of gestational administration of a flavanoid against in utero
Sherin Jacob et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 69, 88-96 (2018-07-17)
Methyl mercury is a teratogenic and neurodevelopmental toxicant in the environment. MeHg affects several biological pathways critical for brain development. The present study validated the effect of Fisetin on developmental MeHg exposure induced alterations in mitochondrial apoptotic pathway and Rho
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