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Merck
CN

46826

Sulfamerazine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide, N1-(4-Methylpyrimidin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O2S
CAS Number:
127-79-7
Molecular Weight:
264.30
Beilstein:
249133
EC Number:
204-866-2
MDL number:
MFCD00023212
UNSPSC Code:
41116107
PubChem Substance ID:
329757246
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

200

Agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

QPPBRPIAZZHUNT-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide
Sulfamerazine is a sulfonamide antibiotic, used mainly to prevent bacterial infections in both humans and animals.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamerazine may be used as a reference standard for the determination of sulfonamide antibiotics in animal muscle, liver and kidney tissues using cation exchange reversed phase sorbent for sample clean-up and analysis by high performance liquid chromatography with diode array detection.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN0013
BCCF1482
BCCC4027
BCBS3635V

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Solubility and solution thermodynamics of sulfamerazine and sulfamethazine in some ethanol+ water mixtures.
Delgado DR, et al.
Fluid Phase Equilibria, 360, 88-96 (2013)
Determination of sulfonamides in animal tissues using cation exchange reversed phase sorbent for sample cleanup and HPLC-DAD for detection.
Hela W, et al.
Food Chemistry, 83(4), 601-608 (2003)
Florian M Koch et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(13), 3679-3692 (2011-03-03)
The first catalytic asymmetric synthesis of β-sultones is reported. This development has enabled a rapid access to a number of highly enantioenriched biologically interesting sulfonyl and sulfinyl compound classes, which makes use of the inherent ring strain of the four-membered
A practical sulfenylation of 2,5-diketopiperazines.
K C Nicolaou et al.
Angewandte Chemie (International ed. in English), 51(3), 728-732 (2011-12-14)
Yi Li et al.
International journal of pharmaceutics, 415(1-2), 110-118 (2011-06-08)
The ability to detect and quantify polymorphism of pharmaceuticals is critically important in ensuring that the formulated product delivers the desired therapeutic properties because different polymorphic forms of a drug exhibit different solubilities, stabilities and bioavailabilities. The purpose of this
View All Related Papers

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