46865
3-Fluoro-3-deoxy-D-glucose
≥99.0% (TLC)
Synonym(s):
3-Deoxy-3-fluoro-D-glucose
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About This Item
Empirical Formula (Hill Notation):
C6H11FO5
CAS Number:
Molecular Weight:
182.15
PubChem Substance ID:
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
1865171
MDL number:
SMILES string
OC[C@H]1OC(O)[C@H](O)[C@@H](F)[C@@H]1O
InChI
1S/C6H11FO5/c7-3-4(9)2(1-8)12-6(11)5(3)10/h2-6,8-11H,1H2/t2-,3+,4-,5-,6?/m1/s1
InChI key
BUMRBAMACDBPKO-CBPJZXOFSA-N
assay
≥99.0% (TLC)
impurities
≤1% water
mp
115-117 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
storage temp.
2-8°C
Other Notes
19F NMR quantitation of lens aldolase reductase activity
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K Karino et al.
The Journal of biological chemistry, 266(31), 20970-20975 (1991-11-05)
In the present study we have determined the kinetics of 3-deoxy-3-fluoro-D-glucose (3-FG) as a substrate for the aldose reductase reaction in vitro. In addition, we compared the 3-deoxy-3-fluoro-sorbitol (3-FS) production rates from 3-FG in the intact lens using 19F NMR
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