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Merck
CN

47440

Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate

puriss., ≥99.0% (19F-NMR)

Synonym(s):

TFFH

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About This Item

Linear Formula:
[FC[=N(CH3)2]N(CH3)2]PF6
CAS Number:
Molecular Weight:
264.12
UNSPSC Code:
12352000
PubChem Substance ID:
MDL number:
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grade

puriss.

assay

≥99.0% (19F-NMR)

mp

104-109 °C (lit.)

storage temp.

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.CN(C)\C(F)=[N+](/C)C

InChI

1S/C5H12FN2.F6P/c1-7(2)5(6)8(3)4;1-7(2,3,4,5)6/h1-4H3;/q+1;-1

InChI key

ZAVXOOLKAGPJPI-UHFFFAOYSA-N

Application

Reagent for synthesis of:
Cationic antimicrobial β-2,2-amino acid derivatives
Philanthotoxin analogues for inhibition of the ionotropic glutamate receptor
Small β-peptidomimetics for antimicrobials
Amine prodrugs of selective neuronal nitric oxide synthase inhibitors

Reagent for:
Selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors
Hydrazone ligation to assemble multifunctional viral nanoparticles

Other Notes

Reagent for preparing Fmoc-amino acid fluorides free of racemization

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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A. El-Faham
Organic preparations and procedures international, 30, 477-477 (1998)
L.A. Carpino et al.
Journal of the American Chemical Society, 117, 5401-5401 (1995)

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