47733
5-Formylsalicylic acid
purum, ≥95.0% (T)
Synonym(s):
2-Hydroxy-5-formylbenzoic acid
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About This Item
Linear Formula:
HCOC6H3-2-(OH)CO2H
CAS Number:
Molecular Weight:
166.13
EC Number:
210-492-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
2640881
MDL number:
Assay:
≥95.0% (T)
Form:
powder
InChI key
UTCFOFWMEPQCSR-UHFFFAOYSA-N
InChI
1S/C8H6O4/c9-4-5-1-2-7(10)6(3-5)8(11)12/h1-4,10H,(H,11,12)
SMILES string
OC(=O)c1cc(C=O)ccc1O
grade
purum
assay
≥95.0% (T)
form
powder
color
brownish-yellow
mp
250 °C (dec.) (lit.)
General description
5-Formylsalicylic acid (5-FSA) is a derivative salicylic acid. It participates in the formation of chelation ion exchange resins. The reaction of 5-FPA with activated methylene compounds has been studied.
Application
5-Formylsalicylic acid may be used in the synthesis of 5-(benzimidazolium-2-yl)salicylate by reacting with o-phenylenediamine.
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Cinnamoylnitrile-, pyran-, and pyranopyrazole-derivatives containing the salicylanilide moiety with anticipated molluscicidal activity.
Nawwar GAM, et al.
Arch. Pharm. (Weinheim), 324(11), 875-877 (1991)
5-Formylsalicylic acid and 5-(benzimidazolium-2-yl) salicylate.
Lu YB, et al.
Acta Crystallographica Section C, Structural Chemistry, 66(12), o596-o599 (2010)
Metal Uptake Properties of Polystyrene Resin Immobilized Polyamine and Formylsalicylic Acid Derivatives as Chelation Ion Exchangers.
Mahmoud ME, et al.
Analytical Sciences, 13(5), 765-769 (1997)
Manabu Nakazono et al.
Clinica chimica acta; international journal of clinical chemistry, 436, 27-34 (2014-05-13)
Various styrylbenzene compounds were synthesized and evaluated as mainly Aβ amyloid sensors. These compounds, however, cannot be used for detecting amyloid deposition in peripheral nerves because of the inherent sensitivity of the compounds. These compounds often generate false positives especially
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