49130
D-(+)-Glucosamine hydrochloride
≥99.0% (HPLC)
Synonym(s):
2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
Molecular Weight:
215.63
EC Number:
200-638-1
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
4157370
assay
≥99.0% (HPLC)
optical activity
[α]20/D +72.5±2°, 24 hr, c = 2% in H2O
ign. residue
≤0.05%
mp
190-194 °C (dec.) (lit.), ≥300 °C
solubility
H2O: 0.1 g/mL, clear, colorless
SMILES string
Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
InChI key
QKPLRMLTKYXDST-NSEZLWDYSA-N
Biochem/physiol Actions
Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.
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Oshra Betzer et al.
ACS nano, 8(9), 9274-9285 (2014-08-19)
A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a
Ji-Sun Hwang et al.
Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)
This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)
Khadijeh Jamialahmadi et al.
Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)
Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in