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Merck
CN

49630

Sigma-Aldrich

Glutaraldehyde solution

technical, ~25% in H2O (2.6 M)

Synonym(s):

Glutaric dialdehyde solution, Pentane-1,5-dial

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About This Item

Linear Formula:
OHC(CH2)3CHO
CAS Number:
111-30-8
Molecular Weight:
100.12
Beilstein:
605390
MDL number:
MFCD00007025
UNSPSC Code:
12352201
PubChem Substance ID:
329757495

Key Documents

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grade

technical

concentration

~25% in H2O (2.6 M)

refractive index

n20/D 1.372

density

1.058 g/mL at 20 °C

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

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General description

Glutaraldehyde solution is 25% solution of glutaraldehyde in water. Antibacterial action of 2% solution of alkaline glutaraldehyde against various atypical mycobacteria has been investigated.

Application

Glutaraldehyde may be used in the following studies:
  • To compose the fixative solution (Glutaraldehyde + Paraformaldehyde + NaPO4) for use in high-resolution light microscopy and electron microscopy studies.
  • To study the conjugation of goat anti-horseradish peroxidase with alkaline phosphatase by a reported method.
  • To compose the primary fixative, which is employed to protect the deterioration of cytoplasmic features of yeast cells during permanganate fixation.

Disclaimer

may contain precipitate

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH071

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Preservation of fine structures in yeast by fixation in a dimethyl sulfoxide-acrolein-glutaraldehyde solution.
D W Schwab et al.
Stain technology, 45(4), 143-147 (1970-07-01)
Plastic Embedding and Sectioning of Plant Tissues.
Liu T.
Bio-protocol, 2(23) (2012)
G Pluschke et al.
Infection and immunity, 51(1), 286-293 (1986-01-01)
The lipopolysaccharide (LPS) of Escherichia coli O18 isolated from a wide variety of sources was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Four different LPS types, designated O18A, O18A1, O18B, and O18B1, were identified. Most O18 strains possess O18A
F M Collins
The Journal of applied bacteriology, 61(3), 247-251 (1986-09-01)
The mycobactericidal activity of 2% alkaline glutaraldehyde solution was determined using standardized suspensions of 10 species of atypical mycobacteria and compared with that for virulent Mycobacterium tuberculosis. Suspensions of M. avium, M. intracellulare and M. gordonae were more resistant to
Stéphane Jauréguiberry et al.
Blood, 124(2), 167-175 (2014-05-27)
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
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