Skip to Content
Merck
CN

50070

Glycinamide hydrochloride

≥99.0% (AT)

Synonym(s):

2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
NH2CH2CONH2 · HCl
CAS Number:
1668-10-6
Molecular Weight:
110.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
329757566
EC Number:
216-789-1
Beilstein/REAXYS Number:
3554199
MDL number:
MFCD00013008
Assay:
≥99.0% (AT)
Form:
solid

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Glycinamide hydrochloride, ≥99.0% (AT)

InChI key

WKNMKGVLOWGGOU-UHFFFAOYSA-N

InChI

1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H

SMILES string

Cl.NCC(N)=O

assay

≥99.0% (AT)

form

solid

pKa (20 °C)

8.20

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.5 M in H2O

UV absorption

λ: 260 nm Amax: 0.1

functional group

amide
amine

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Glycinamide hydrochloride may be used in the synthesis of [M(glycinamidato-N,N′)(ptpy)2] where ptpy = 2-(p-tolyl)pyridinato) and M= Rh or Ir.
It may be used in the synthesis of the following glycinamide-based imidazolidinones:
  • (±)-2-(2-phenylpropyl)imidazolidin-4-one
  • (±)-2-(2,4,4-trimethylpentyl)imidazolidin-4-one
  • (±)-2-[(R)-2,6-dimethyl-5-heptenyl]imidazolidin-4-one
  • (5R,6S,9R)-6-isopropyl-9-methyl-1,4-diazaspiro[4.5]decan-2-one
  • (5S,6S,9R)-6-isopropyl-9-methyl-1,4-diazaspiro[4.5]decan-2-one
  • (±)-2-methyl-2-pentylimidazolidin-4-one
  • (±)-2-ethyl-2-(2-methylbutyl)imidazolidin-4-one
  • (±)-2-(undecan-2-yl)imidazolidin-4-one
  • (±)-2-pentylimidazolidin-4-one
  • 2-(2,4-dimethylcyclohex-3-en-1-yl)imidazolidin-4-one

Other Notes

Use in peptide coupling.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN4402
BCCM4703
BCCL0989
BCCH1271
BCCH7087

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

N.J. Miles et al.
Journal of the Chemical Society. Perkin Transactions 1, 2299-2299 (1985)
Preparation of Imidazolidin-4-ones and Their Evaluation as Hydrolytically Cleavable Precursors for the Slow Release of Bioactive Volatile Carbonyl Derivatives.
Trachsel A, et al.
European Journal of Organic Chemistry, 2012(14), 2837-2854 (2012)
Synthesis and Characterization of New Bis-Cyclometalated Rhodium and Iridium Complexes Containing the Glycinamidato Ligand.
Graf M, et al.
Zeitschrift fur Anorganische und Allgemeine Chemie, 639(7), 1117-1121 (2013)
Controlled gelation and sintering of monolithic gels prepared from g-alumina fume powder.
Tsai DS and Hsieh CC.
Journal of the American Ceramic Society. American Ceramic Society, 74(4), 830-836 (1991)
Gottfried K Schroeder et al.
Biochemistry, 46(13), 4037-4044 (2007-03-14)
As a model for mechanistic comparison with peptidyl transfer within the ribosome, the reaction of aqueous glycinamide with N-formylphenylalanine trifluoroethyl ester (fPhe-TFE) represents an improvement over earlier model reactions involving Tris. The acidity of trifluoroethanol (pKa 12.4) resembles that of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service