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Merck
CN

50110

Glycine methyl ester hydrochloride

puriss., ≥99.0% (AT)

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About This Item

Linear Formula:
NH2CH2COOCH3 · HCl
CAS Number:
Molecular Weight:
125.55
EC Number:
227-139-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3593644
MDL number:
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InChI key

COQRGFWWJBEXRC-UHFFFAOYSA-N

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H

SMILES string

Cl.COC(=O)CN

grade

puriss.

assay

≥99.0% (AT)

ign. residue

≤0.05%

mp

175 °C (dec.) (lit.), 175-176 °C (dec.)

Regulatory Information

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D Solís et al.
Analytical biochemistry, 209(1), 117-122 (1993-02-15)
The usefulness of ricin as a research tool is handicapped by its extremely biohazardous nature. In this work, ricin toxicity has been reduced by chemical modification of carboxyl groups using 1-ethyl-3(3-dimethylaminopropyl) carbodiimide and [14C]glycine methyl ester. The reaction was carried
J M Delfino et al.
International journal of peptide and protein research, 21(4), 440-450 (1983-04-01)
The reactivity of the carboxyl groups in bovine growth hormone was studied by reaction with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide in the presence of an excess of glycinemethylester. Localization in the molecule of the various kinetically distinguishable carboxyl groups was achieved. Highest reactivity
Vincenzo Santagada et al.
Journal of combinatorial chemistry, 7(4), 618-621 (2005-07-12)
An easy and convenient microwave-assisted synthesis of N-alkylated glycine methyl esters is described. Parallel and nonparallel combinatorial methods are described and compared. The described reactions are reductive alkylations of several aldehydes and glycine methyl ester in the presence of NaBH3CN.
M Iwama et al.
Biological & pharmaceutical bulletin, 24(9), 978-981 (2001-09-18)
The sialic acid binding lectin from bullfrog Rana catesbeiana oocyte (cSBL) is known to have anti-tumor activity. In order to investigate the relationship between the net charge of cSBL and its anti-tumor effect, cSBL was modified with a water-soluble carbodiimide
L K Frankel et al.
Biochemistry, 38(43), 14271-14278 (1999-11-26)
The effects of the modification of carboxylate groups on the manganese-stabilizing protein of photosystem II were investigated. Carboxylate groups (including possibly the C-terminus) on the manganese-stabilizing protein were modified with glycine methyl ester in a reaction facilitated by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The

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