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50513

18β-Glycyrrhetinic acid potassium salt

≥96.0% (HPLC)

Synonym(s):

Enoxolone potassium salt

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About This Item

Empirical Formula (Hill Notation):
C30H45KO4
CAS Number:
85985-61-1
Molecular Weight:
508.77
UNSPSC Code:
12352200
PubChem Substance ID:
24873372
MDL number:
MFCD01863062
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assay

≥96.0% (HPLC)

SMILES string

[K+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C([O-])=O

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18β-Glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.
Sharma G, Kar S, Palit S, Das PK.
Journal of Cellular Physiology, 227(5), 1923-1931 (2011)
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Anticancer research, 31(6), 2209-2215 (2011-07-09)
UVB radiation is the major etiological factor in the pathogenesis of skin aging and cancer development. New approaches to prevent and reverse UVB damage are needed to reduce sunlight-induced skin cancer. This study aimed to investigate a possible protective activity
Andrew Sunters et al.
The Journal of biological chemistry, 278(50), 49795-49805 (2003-10-07)
Paclitaxel is used to treat breast cancers, but the mechanisms by which it induces apoptosis are poorly understood. Consequently, we have studied the role of the FoxO transcription factors in determining cellular response to paclitaxel. Western blotting revealed that in
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