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Merck
CN

50590

Sigma-Aldrich

Glycolic acid

≥97.0% (T)

Synonym(s):

Hydroxyacetic acid

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About This Item

Linear Formula:
HOCH2COOH
CAS Number:
79-14-1
Molecular Weight:
76.05
Beilstein:
1209322
EC Number:
201-180-5
MDL number:
MFCD00004312
UNSPSC Code:
12352100
eCl@ss:
39021303
PubChem Substance ID:
329757610

Key Documents

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Assay

≥97.0% (T)

impurities

~1% water

mp

75-80 °C (lit.)
75-80 °C

solubility

H2O: 0.1 g/mL, clear

SMILES string

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

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General description

Glycolic acid, also known as α-hydroxy acetic acid (AHA), is commonly used in chemical peels.

Application

Glycolic acid may be used in the preparation of glycolide, a monomer for preparing poly(glycolic acid) (PGA).

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H332

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

>572.0 °F - (decomposition)

Flash Point(C)

> 300 °C - (decomposition)

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Glycolic acid peels for the treatment of wrinkles and photoaging.
Moy LS, et al.
The Journal of Dermatologic Surgery and Oncology, 19(3), 243-246 (1993)
F F Becker et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 22(5), 463-465 (1996-05-01)
Seventy percent glycolic acid solutions are being commonly used as superficial chemical peeling agents. The pH of these solutions ranges from 0.08 to 2.75. The histologic effects of these various pH solutions on human skin have not been studied. The
N Wang et al.
Journal of biomaterials science. Polymer edition, 8(12), 905-917 (1997-01-01)
A series of oligomers or low molecular weight polymers of lactic and/or glycolic acid has been synthesized with different molar ratios of lactic to glycolic acid. These oligomers have been characterized with respect to oligomer composition, molecular weight, intrinsic viscosity
L Atzori et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 12(2), 119-122 (1999-05-27)
Glycolic acid chemical peels have been widely accepted as a useful modality in many cutaneous conditions characterized by abnormalities of keratinization. The aim of this study is to evaluate the use of glycolic peels in the main clinical forms of
Sharma SK, et al.
A Handbook of Applied Biopolymer Technology: Synthesis, Degradation and Applications., 153-153 (2011)
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