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Merck
CN

51113

Guanosine 5′-[β-thio]diphosphate trilithium salt

90-95% (HPLC)

Synonym(s):

GDPβS trilithium salt, GDP-β-S, GDP-β-S-Li3

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About This Item

Empirical Formula (Hill Notation):
C10H12Li3N5O10P2S
CAS Number:
97952-36-8
Molecular Weight:
477.07
EC Number:
308-328-9
UNSPSC Code:
41106305
MDL number:
MFCD00057735
Beilstein/REAXYS Number:
8181243

Key Documents

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InChI key

LMCWQGPJYZRMKU-CYCLDIHTSA-K

InChI

1S/C10H15N5O10P2S.3Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1

SMILES string

[Li+].[Li+].[Li+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C(=O)N1

assay

90-95% (HPLC)

impurities

~14% water

shipped in

wet ice

storage temp.

−20°C

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Other Notes

Competitively inhibits the stimulation of adenylate cyclase activity by GTP and fluoride

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Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
F Eckstein et al.
The Journal of biological chemistry, 254(19), 9829-9834 (1979-10-10)

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