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Merck
CN

51362

Supelco

Auramine

analytical standard

Synonym(s):

4,4′-Dimethylaminobenzophenone imine, Solvent Yellow 34

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About This Item

Empirical Formula (Hill Notation):
C17H21N3
CAS Number:
492-80-8
Molecular Weight:
267.37
Colour Index Number:
41000B
Beilstein:
2215338
EC Number:
207-762-5
MDL number:
MFCD00036224
UNSPSC Code:
85151701
PubChem Substance ID:
329757682
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥97.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

CN(C)c1ccc(cc1)C(=N)c2ccc(cc2)N(C)C

InChI

1S/C17H21N3/c1-19(2)15-9-5-13(6-10-15)17(18)14-7-11-16(12-8-14)20(3)4/h5-12,18H,1-4H3

InChI key

JPIYZTWMUGTEHX-UHFFFAOYSA-N

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General description

Auramine is a diphenylmethane dye, used in fluorescence microscopy.

Application

Auramine-phenol fluorochrome staining technique can be used to detect Mycobacterium tuberculosis in sputum, cerebrospinal fluid and other specimens. It may be used as a reference standard in the determination of auramine in processed foods using high-performance liquid chromatography (HPLC).
Auramine-phenol fluorochrome staining technique can be used to detect Mycobacterium tuberculosis in sputum, cerebrospinal fluid and other specimens. It may be used as a reference standard in the determination of auramine in processed foods using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Signal Word

Warning

Hazard Statements

H302,H319,H351,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8394
BCCC9892
BCBT4194

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Synne Jenum et al.
Scientific reports, 6, 18520-18520 (2016-01-05)
The World Health Organization (WHO) calls for an accurate, rapid, and simple point-of-care (POC) test for the diagnosis of pediatric tuberculosis (TB) in order to make progress "Towards Zero Deaths". Whereas the sensitivity of a POC test based on detection
Elisabetta Walters et al.
Archives of disease in childhood, 99(11), 998-1003 (2014-06-19)
Early initiation of antiretroviral therapy (ART) in HIV-infected infants reduces mortality and opportunistic infections including tuberculosis (TB). However, young HIV-infected children remain at high risk of TB disease following mycobacterial infection. We document the spectrum of TB disease in HIV-infected
Fei Huang et al.
Emerging infectious diseases, 25(7), 1289-1296 (2019-06-19)
The increase in drug-resistant tuberculosis in China calls for scaling up rapid diagnosis. We evaluated introduction of rapid resistance testing by line-probe assay for all patients with a diagnosis of pulmonary tuberculosis in 2 prefectures in middle and eastern China.
Yang-Hee Kim et al.
Nature communications, 11(1), 1365-1365 (2020-03-15)
Nanoclays have generated interest in biomaterial design for their ability to enhance the mechanics of polymeric materials and impart biological function. As well as their utility as physical cross-linkers, clays have been explored for sustained localization of biomolecules to promote in
Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review.
Steingart RK, et al.
The Lancet Infectious Diseases, 6(9), 570-581 (2006)
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