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Merck
CN

51465

Urea

tested according to Ph. Eur.

Synonym(s):

Ureum, Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
57-13-6
Molecular Weight:
60.06
EC Number:
200-315-5
UNSPSC Code:
12352200
PubChem Substance ID:
329757692
Beilstein/REAXYS Number:
635724
MDL number:
MFCD00008022
Assay:
98.5-101.5% (Dried Substance)

Key Documents

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agency

USP/NF, tested according to Ph. Eur.

assay

98.5-101.5% (Dried Substance)

form

solid

mp

132-135 °C (lit.)

solubility

H2O: soluble 480 g/L at 20 °C (completely)

density

1.335 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

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Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT3953

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G L French et al.
Lancet (London, England), 2(8551), 117-119 (1987-07-18)
Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography/mass spectrometry with selected ion monitoring in cerebrospinal fluid (CSF) from 13 patients with proven and 8 out of 9 patients with suspected tuberculous meningitis; the negative result
Sreenivasa C Ramaiahgari et al.
Archives of toxicology, 88(5), 1083-1095 (2014-03-07)
Immortalized hepatocyte cell lines show only a weak resemblance to primary hepatocytes in terms of gene expression and function, limiting their value in predicting drug-induced liver injury (DILI). Furthermore, primary hepatocytes cultured on two-dimensional tissue culture plastic surfaces rapidly dedifferentiate
Thi-Mai Anh Dao et al.
PloS one, 6(6), e20700-e20700 (2011-06-16)
Resveratrol (RSV) is a potent anti-diabetic agent when used at high doses. However, the direct targets primarily responsible for the beneficial actions of RSV remain unclear. We used a formulation that increases oral bioavailability to assess the mechanisms involved in
A mechanically and electrically self-healing supercapacitor.
Hua Wang et al.
Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)
Oliver C Witard et al.
Brain, behavior, and immunity, 39, 211-219 (2013-10-15)
The present study examined whether a high protein diet prevents the impaired leukocyte redistribution in response to acute exercise caused by a large volume of high-intensity exercise training. Eight cyclists (VO2max: 64.2±6.5mLkg(-1)min(-1)) undertook two separate weeks of high-intensity training while
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Global Trade Item Number

SKUGTIN
1547379-200MG04061833853535
1534413-50MG04061833853429
1547380-200MG04061833853542
1547391-200MG04061833853559
1547459-200MG04061833853573
1547550-200MG04061833853580
1547903-200MG04061833853603
1551150-300MG04061833853610

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