51681
Silychristin
analytical standard
Synonym(s):
Silymarin II
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About This Item
Empirical Formula (Hill Notation):
C25H22O10
CAS Number:
Molecular Weight:
482.44
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
251-720-9
MDL number:
grade
analytical standard
Quality Level
assay
≥90.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤10.0% water
application(s)
food and beverages
format
neat
storage temp.
2-8°C
SMILES string
COc1cc(ccc1O)[C@@H]2Oc3c(O)cc(cc3[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
InChI
1S/C25H22O10/c1-33-18-6-10(2-3-15(18)28)23-14(9-26)13-4-11(5-17(30)25(13)35-23)24-22(32)21(31)20-16(29)7-12(27)8-19(20)34-24/h2-8,14,22-24,26-30,32H,9H2,1H3/t14-,22+,23+,24-/m1/s1
InChI key
BMLIIPOXVWESJG-LMBCONBSSA-N
General description
Silychristin is one of the congeners of flavonolignan silybin. It is usually derived from silymarin, which is extracted from the fruits of Silybum marianum (L.) Gaertn, and Asteraceae (Carduus marianus L.; milk thistle).
Application
Silychristin may be used as an analytical reference standard for the determination of silychristin in:
- Herbal extracts, fruit extracts, and seed extracts of Silybum marianum by ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD) and methanol extraction coupled to HPLC equipped with ultraviolet array detection (UVAD).
- Milk thistle seeds by HPLC-UV.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Pharmacokinetics of pure silybin diastereoisomers and identification of their metabolites in rat plasma.
Marhol P, et al.
Journal of functional foods, 14, 570-580 (2015)
Phytochemical analysis, molecular docking and antiamnesic effects of methanolic extract of Silybum marianum (L.) Gaertn seeds in scopolamine induced memory impairment in mice.
Nazir N, et al.
Journal of Ethnopharmacology, 210(7), 198-208 (2018)
Wendy A Smith et al.
Planta medica, 71(9), 877-880 (2005-10-06)
A new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. This was shown by NMR spectroscopy to be silychristin B (8), a diastereoisomer of the known silychristin (7). Levels of these and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 51681-10MG | 04061832534596 |