52512
1,1,1,3,3,3-Hexafluoro-2-propanol
puriss., ≥99.0% (GC)
Synonym(s):
HFP, Hexafluoroisopropanol
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About This Item
Linear Formula:
(CF3)2CHOH
CAS Number:
Molecular Weight:
168.04
EC Number:
213-059-4
UNSPSC Code:
12352104
PubChem Substance ID:
Beilstein/REAXYS Number:
1841007
MDL number:
Assay:
≥99.0% (GC)
grade
puriss.
assay
≥99.0% (GC)
impurities
≤0.1% water
refractive index
n20/D 1.275 (lit.)
bp
59 °C (lit.)
mp
−4 °C (lit.)
density
1.596 g/mL at 25 °C (lit.)
SMILES string
OC(C(F)(F)F)C(F)(F)F
InChI
1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H
InChI key
BYEAHWXPCBROCE-UHFFFAOYSA-N
Other Notes
Solvent with high solubilizing potential for peptides and peptide intermediates
This product has been replaced by 105228-ALDRICH | 1,1,1,3,3,3-Hexafluoro-2-propanol ≥99%
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2 Oral
target_organs
Central nervous system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
No data available
flash_point_c
No data available
ppe
Faceshields, Gloves, Goggles
Regulatory Information
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L M Jungbauer et al.
Journal of molecular recognition : JMR, 22(5), 403-413 (2009-04-04)
Recent research has focused on soluble oligomeric assemblies of the 42 amino acid isoform of the amyloid-beta peptide (A beta 42) as the proximal cause of neuronal injury, synaptic loss, and the eventual dementia associated with Alzheimer's disease (AD). While
Thomas J Esparza et al.
Annals of neurology, 73(1), 104-119 (2012-12-12)
Although amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer disease; soluble oligomeric Aβ has been hypothesized to more directly underlie impaired learning and memory in dementia of the Alzheimer type. However, the lack of a
M. Narita et al.
Bulletin of the Chemical Society of Japan, 61, 281-281 (1988)