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Merck
CN

53320

L-Histidine

≥99.0% (NT)

Synonym(s):

(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
71-00-1
Molecular Weight:
155.15
EC Number:
200-745-3
UNSPSC Code:
12352209
MDL number:
MFCD00064315
Beilstein/REAXYS Number:
84088

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InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

assay

≥99.0% (NT)

optical activity

[α]20/D −39±1°, c = 2% in H2O

impurities

≤0.5% foreign amino acids

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying, 110 °C

mp

282 °C (dec.) (lit.), ~285 °C (dec.)

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, NH4+: ≤500 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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Biochem/physiol Actions

Precursor of histamine by action of histidine decarboxylase.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Pawel Swietach et al.
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Biopolymers, 91(12), 1064-1082 (2009-06-19)
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Science (New York, N.Y.), 340(6138), 1346-1349 (2013-06-15)
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Proceedings of the National Academy of Sciences of the United States of America, 111(16), 6022-6027 (2014-04-09)
The genome packaging reactions of tailed bacteriophages and herpes viruses require the activity of a terminase enzyme, which is comprised of large and small subunits. Phage genomes are replicated as linear concatemers composed of multiple copies of the genome joined
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