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53633

Glabridin

analytical standard

Synonym(s):

(R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol

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About This Item

Empirical Formula (Hill Notation):
C20H20O4
CAS Number:
59870-68-7
Molecular Weight:
324.37
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329757962
MDL number:
MFCD03427694
Beilstein/REAXYS Number:
7141956
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grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

CC1(C)Oc2ccc3C[C@@H](COc3c2C=C1)c4ccc(O)cc4O

InChI

1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1

InChI key

LBQIJVLKGVZRIW-ZDUSSCGKSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

512.6 °F - closed cup

flash_point_c

267 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF6975
BCCB2192
BCBZ3931
BCBF0498V
BCBF0498

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Eun Mi Choi
Chemico-biological interactions, 193(1), 71-78 (2011-05-31)
Mitochondrial dysfunction, particularly respiratory chain disruption, is often responsible for aging-related bone diseases. In this study, the protective effects of glabridin, an isoflavan isolated from licorice root, against pharmacological inhibition of the respiratory chain were studied using osteoblastic MC3T3-E1 cells
Dana Atrahimovich et al.
Journal of agricultural and food chemistry, 60(14), 3679-3685 (2012-03-03)
The enzyme paraoxonase 1 (PON1) binds to high-density lipoprotein (HDL) and is responsible for many of HDL's antiatherogenic properties. We previously showed that recombinant PON1 is inhibited by linoleic acid hydroperoxide (LA-OOH) present in the lipid fraction of the human
Sun Hong Park et al.
Phytotherapy research : PTR, 24 Suppl 1, S29-S34 (2009-05-21)
Glabridin, a flavonoid present in licorice root, is known to have antiinflammatory and cardiovascular protective activities. The present study reports an inhibitory effect of glabridin on microglial activation. Glabridin dose-dependently attenuated lipopolysaccharide (LPS)-induced production of inflammatory mediators, including nitric oxide
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Global Trade Item Number

SKUGTIN
53633-10MG04061833238134