55968
6-Hydroxypyridine-3-carboxylic acid
purum, ≥98.0% (HPLC)
Synonym(s):
2-Hydroxy-5-pyridinecarboxylic acid, 6-Hydroxynicotinic acid
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About This Item
Empirical Formula (Hill Notation):
C6H5NO3
CAS Number:
Molecular Weight:
139.11
EC Number:
225-682-9
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
115991
MDL number:
grade
purum
assay
≥98.0% (HPLC)
mp
>300 °C (lit.)
SMILES string
OC(=O)c1ccc(O)nc1
InChI
1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChI key
BLHCMGRVFXRYRN-UHFFFAOYSA-N
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Ashish Gupta et al.
NMR in biomedicine, 18(5), 293-299 (2005-03-11)
The utility of (1)H NMR spectroscopy is suggested and demonstrated for the diagnosis of Pseudomonas aeruginosa in urinary tract infection (UTI). The specific property of P. aeruginosa of metabolizing nicotinic acid to 6-hydroxynicotinic acid (6-OHNA) is exploited. The quantity of
Li Xu et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 46(1), 63-67 (2006-04-04)
The current technology for microbial hydroxylation of nicotinic acid is a procedure of resting cells transformation. Here it was reported that non-degradation of 6-hydroxynicotinic acid during hydroxylation of nicotinic acid by resting cells was due to existing of nicotinic acid
C L Kitts et al.
Journal of bacteriology, 174(23), 7791-7797 (1992-12-01)
A complete pathway for Azorhizobium caulinodans nicotinate catabolism has been determined from mutant phenotype analyses, isolation of metabolic intermediates, and structural studies. Nicotinate serves as a respiratory electron donor to O2 via a membrane-bound hydroxylase and a specific c-type cytochrome
S Shiraishi et al.
Journal of chromatography, 338(1), 51-59 (1985-02-27)
Gas chromatography--mass spectrometry has been used to identify specific metabolites produced by Gram-negative bacteria such as Pseudomonas aeruginosa, Serratia marcescens, Klebsiella pneumoniae and Escherichia coli in a defined medium. 6-Hydroxynicotinic acid was detected in spent culture media of Pseudomonas aeruginosa
Yao Yang et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 48(1), 112-115 (2008-03-15)
Recently, new insecticides containing 3-chloropyridylmethyl group as a versatile building block have been developed, among which imidachloprid is a promising one. The synthesis of imidachloprid can use 6-Hydroxynicotinic acid, the first intermediate of the bacterial degradation of nicotinic acid, as
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