56198
3-Hydroxypicolinic acid
purum, ≥96.0% (T)
Synonym(s):
3-HPA, 3-Hydroxypyridine-2-carboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C6H5NO3
CAS Number:
Molecular Weight:
139.11
EC Number:
212-859-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
118954
MDL number:
InChI key
BRARRAHGNDUELT-UHFFFAOYSA-N
InChI
1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)
SMILES string
OC(=O)c1ncccc1O
grade
purum
assay
≥96.0% (T)
mp
213-218 °C (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Jason P Schrum et al.
Journal of the American Chemical Society, 131(40), 14560-14570 (2009-09-18)
The development of a sequence-general nucleic acid copying system is an essential step in the assembly of a synthetic protocell, an autonomously replicating spatially localized chemical system capable of spontaneous Darwinian evolution. Previously described nonenzymatic template-copying experiments have validated the
Chih-Chi Chu et al.
Chembiochem : a European journal of chemical biology, 15(13), 1905-1910 (2014-07-25)
We report DNA catalysts (deoxyribozymes) that join tyrosine-containing peptides to RNA and DNA in one step and without requiring protecting groups on either the peptide or the nucleic acid. Our previous efforts towards this goal required tethering the peptide to
K Tang et al.
Rapid communications in mass spectrometry : RCM, 8(9), 673-677 (1994-09-01)
We found that picolinic acid is a very good matrix for matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry of oligonucleotides, proteins and tRNA. Among the oligonucleotides, picolinic acid was shown to be effective for homo-oligonucleotides, d(G)40 and d(C)60, and for
E Nordhoff et al.
Nucleic acids research, 22(13), 2460-2465 (1994-07-11)
UV-matrix assisted laser desorption/ionization mass spectrometry (UV-MALDI-MS) with 3-hydroxypicolinic acid as matrix and IR-MALDI-MS with succinic acid as matrix have proved their feasibility for highly accurate and sensitive mass determination of nucleic acids (DNA and RNA). In this work, a
J M Koomen et al.
Journal of mass spectrometry : JMS, 35(8), 1025-1034 (2000-09-06)
The changes in the ion signals in the isotope cluster, mass resolution, signal-to-noise ratio and mass accuracy for matrix-assisted laser desorption/ionization (MALDI) of DNA oligonucleotides (dGGATC, dCAGCt, and dAACCGTT) and their fragment ions were evaluated, and these data were compared
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