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Merck
CN

56570

5-Hydroxy-L-tryptophan

≥99.0% (calc. based on dry substance, NT)

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O3
CAS Number:
Molecular Weight:
220.22
EC Number:
224-411-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
88200
MDL number:
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assay

≥99.0% (calc. based on dry substance, NT)

optical activity

[α]20/D −33±2°, c = 1% in H2O

ign. residue

≤0.05%

loss

≤2% loss on drying

refractive index

n20/D 1.4850 (lit.)

mp

270 °C (dec.) (lit.), ~275 °C (dec.)

density

0.902 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(O)=O

InChI

1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1

InChI key

LDCYZAJDBXYCGN-VIFPVBQESA-N

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Other Notes

Substrate of choice for the assay of aromatic L-amino acid decarboxylase

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W. Lovenberg
Methods in Enzymology, 17A, 652-652 (1970)
Deepali Gupta et al.
European journal of pharmacology, 735, 59-67 (2014-04-22)
Depression and anxiety are the most debilitating mood disorders with poor therapeutic recovery rates. In the last decades, 5-HT3 receptor antagonists have been identified as potential agents for mood disorders. The current investigation focuses on evaluating the, antidepressant and anti-anxiety
Maryam Goudarzi et al.
Radiation and environmental biophysics, 53(4), 645-657 (2014-07-23)
Metabolomics has been shown to have utility in assessing responses to exposure by ionizing radiation (IR) in easily accessible biofluids such as urine. Most studies to date from our laboratory and others have employed γ-irradiation at relatively high dose rates
Robert Haberzettl et al.
Behavioural brain research, 277, 204-210 (2014-05-02)
In humans, the ingestion of the combination of two or more serotonin (5-HT)-enhancing drugs but also of a single drug in overdose can induce serious adverse effects, which are characteristics of the serotonin syndrome (SS). In mice, acute administration of

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