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Merck
CN

57730

2-Iodobenzoic acid

purum, ≥95.0% (GC)

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About This Item

Linear Formula:
IC6H4CO2H
CAS Number:
Molecular Weight:
248.02
EC Number:
201-850-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1861406
MDL number:
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grade

purum

assay

≥95.0% (GC)

ign. residue

≤0.5%

mp

160-162 °C (lit.), 161-164 °C

SMILES string

OC(=O)c1ccccc1I

InChI

1S/C7H5IO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)

InChI key

CJNZAXGUTKBIHP-UHFFFAOYSA-N

Other Notes

Starting material for the preparation of iodosobenzoate, a useful oxidant. Protecting group for alcohols, the esters are cleaved oxidatively


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R.A. Moss et al.
Tetrahedron Letters, 28, 5005-5005 (1987)
M Láznícek et al.
General physiology and biophysics, 2(4), 279-285 (1983-08-01)
125I-labelled o-iodobenzoate (OIB) was prepared by means of an isotopic exchange reaction; its distribution and excretion were determined and its pharmacokinetic parameters in rats were calculated. The calculated value of the half-life of OIB elimination was 38.7 +/- 0.7 min
T Kugimiya et al.
The Tohoku journal of experimental medicine, 144(3), 315-320 (1984-11-01)
We studied the effect of ortho-iodo sodium benzoate (OISB) given intraperitoneally to mice. 300 and 600 mg/kg of OISB increased P50 from the control value of 41.2 mmHg to 42.7 mmHg and 45.7 mmHg, respectively. The mice were then exposed