58775
Isocitric Dehydrogenase (NADP) from porcine heart
3-8 U/mg protein (~12 mg/ml)
Synonym(s):
threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH
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About This Item
CAS Number:
UNSPSC Code:
12352200
EC Number:
232-835-3
MDL number:
form
solution (clear)
specific activity
3-8 U/mg protein (~12 mg/ml)
mol wt
Mr ~61000
color
amber
storage temp.
2-8°C
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Physical form
50% glycerol; EDTA buffer salts, pH ~6.0
Other Notes
1 U corresponds to the amount of enzyme which catalyzes the conversion of 1 μmol isocitrate to α-ketoglutarate at pH 7.4 and 37°C
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Protein tyrosine nitration is a post-translational modification mediated by reactive nitrogen species (RNS) that is associated with nitro-oxidative damage. No information about this process is available in relation to higher plants during development and senescence. Using pea plants at different
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Journal of cancer research and therapeutics, 8(4), 598-601 (2013-01-31)
Mutations in the gene encoding isocitrate dehydrogenase (IDH1) have been reported in gliomas. This study analyses a series of 184 glioma cases in a tissue microarray (TMA)-based approach to assess the frequency of R132H point mutations in formalin-fixed, paraffin-embedded tissue
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