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Merck
CN

60155

Potassium citrate tribasic monohydrate

tested according to Ph. Eur.

Synonym(s):

Kalii citras, Citric acid tripotassium salt, Tripotassium citrate

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About This Item

Linear Formula:
HOC(COOK)(CH2COOK)2 · H2O
CAS Number:
Molecular Weight:
324.41
EC Number:
231-905-0
UNSPSC Code:
12352300
PubChem Substance ID:
Beilstein/REAXYS Number:
3924344
MDL number:
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InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

SMILES string

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

agency

USP/NF, tested according to Ph. Eur.

assay

99-101% anhydrous basis

form

solid

mp

275 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Zeynep Aygun
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 130-133 (2012-12-26)
Electron paramagnetic resonance (EPR) studies of single crystals and powder samples of Cu(2+) and VO(2+) doped potassium dihydrogen citrate (PDHC) have been carried out at different temperatures. The temperature-dependant g and A values have been obtained for powder spectra of
Donna J Claes et al.
Pediatric nephrology (Berlin, Germany), 27(11), 2031-2038 (2012-01-28)
Cystinuria is a relatively uncommon cause of pediatric stone disease, but has significant morbidity if not properly controlled because of its significant stone recurrence rate. Cystinuria is caused by the inability of the renal tubules to reabsorb filtered cystine, which
A comparative pilot study of litholytic properties of Celosia argental (Sitivaraka) versus potassium citrate in renal calculus disease.
Rana G Singh et al.
Journal of alternative and complementary medicine (New York, N.Y.), 18(5), 427-428 (2012-04-28)
Naim M Maalouf et al.
The Journal of clinical endocrinology and metabolism, 96(12), 3733-3740 (2011-10-07)
Dietary intake of animal proteins is associated with an increase in urinary calcium and nephrolithiasis risk. We tested the hypothesis that the acid load imposed by dietary proteins causes this hypercalciuria. In a short-term crossover metabolic study, an alkali salt
Pierre Cochat et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(5), 1729-1736 (2012-05-02)
Primary hyperoxaluria Type 1 is a rare autosomal recessive inborn error of glyoxylate metabolism, caused by a deficiency of the liver-specific enzyme alanine:glyoxylate aminotransferase. The disorder results in overproduction and excessive urinary excretion of oxalate, causing recurrent urolithiasis and nephrocalcinosis.

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