60890
Kojic acid
purum, ≥98.0% (HPLC)
Synonym(s):
2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
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About This Item
Empirical Formula (Hill Notation):
C6H6O4
CAS Number:
Molecular Weight:
142.11
EC Number:
207-922-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
120895
MDL number:
grade
purum
assay
≥98.0% (HPLC)
mp
152-155 °C (lit.)
SMILES string
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
InChI key
BEJNERDRQOWKJM-UHFFFAOYSA-N
Biochem/physiol Actions
Tyrosinase inhibitor.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Ronald Bentley
Natural product reports, 23(6), 1046-1062 (2006-11-23)
This article reviews the curious history of kojic acid, discovered as a fungal natural product in 1907. It was one of the first secondary metabolites to have its biosynthetic pathway studied by the isotope tracer technique, and, more recently, has
Edisson Tello et al.
Journal of natural products, 75(9), 1637-1642 (2012-08-22)
Three new cembranoid diterpenes, knightine (1), 11(R)-hydroxy-12(20)-en-knightal (2), and 11(R)-hydroxy-12(20)-en-knightol acetate (3), were isolated as minor constituents of the Caribbean gorgonian Eunicea knighti, along with the known cembranoids 4-8. The stereostructures of the new compounds were determined by detailed spectroscopic
Hyunjung Choi et al.
Journal of dermatological science, 66(3), 207-215 (2012-04-03)
Kojic acid is a fungal metabolite widely used in medicinal and cosmetic formulations as a skin-lightening agent based on its de-pigmenting activity. Although in human clinical studies kojic acid has been shown to be effective in the treatment of hyper-pigmentation