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Merck
CN

61123

Cresyl Violet acetate

Synonym(s):

9-Amino-5-imino-5H-benzo[a]phenoxazine acetate salt

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About This Item

Empirical Formula (Hill Notation):
C18H15N3O3
CAS Number:
10510-54-0
Molecular Weight:
321.33
EC Number:
234-043-3
UNSPSC Code:
12171500
MDL number:
MFCD00013151

Key Documents

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mp

140-143 °C (lit.)

suitability

suitable for microscopy

SMILES string

CC(O)=O.Nc1cc2OC3=CC(=N)C=CC3=Nc2c4ccccc14

InChI

1S/C16H11N3O.C2H4O2/c17-9-5-6-13-14(7-9)20-15-8-12(18)10-3-1-2-4-11(10)16(15)19-13;1-2(3)4/h1-8,17H,18H2;1H3,(H,3,4)

InChI key

ORIKHDNZZCTIAD-UHFFFAOYSA-N

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Other Notes

For use in fluorescence microscopy (λex 575 nm, λem 620 nm); Redox-indicator dye; Dye used in a coupled fluorometric assay of pyruvate dehydrogenase.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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M Solomon et al.
Analytical biochemistry, 141(2), 337-343 (1984-09-01)
A method for measuring the activity of the pyruvate dehydrogenase complex (PDC) by coupling acetyl-CoA production to acetylation of a fluorescent dye is described. Acetylation of cresyl violet acetate by pigeon liver acetyltransferase results in a shift of its fluorescence
A Alvarez-Buylla et al.
Journal of neuroscience methods, 33(2-3), 129-133 (1990-08-01)
Cresyl violet is widely used by neurobiologists to visualize Nissl substance in bright-field microscopy. Here we describe a method for using this dye as a red fluorescent Nissl stain. Unlike the bright-field staining technique, fluorescent cresyl is compatible with other
J. Ruseler-vanEmbden et al.
FEMS Microbiology Letters, 28, 341-341 (1985)
Estelle Rousselet et al.
Journal of visualized experiments : JoVE, (69)(69), doi:10-doi:10 (2012-11-22)
Stroke is the third cause of mortality and the leading cause of disability in the World. Ischemic stroke accounts for approximately 80% of all strokes. However, the thrombolytic tissue plasminogen activator (tPA) is the only treatment of acute ischemic stroke
Priscilla Hirst et al.
Neural plasticity, 2012, 197264-197264 (2012-07-14)
Recent studies suggest that exposure to only one component of audiovisual events can lead to cross-modal cortical activation. However, it is not certain whether such crossmodal recruitment can occur in the absence of explicit conditioning, semantic factors, or long-term associations.
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