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About This Item
Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
Molecular Weight:
166.65
EC Number:
233-952-2
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4237021
MDL number:
grade
purum
assay
≥99.0% (AT)
optical activity
[α]20/D +10±1°, c = 2% in H2O
optical purity
enantiomeric ratio: ≥99:1 (GC)
mp
245-248 °C, 254-256 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.CC(C)C[C@H](N)C(N)=O
InChI
1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1
InChI key
VSPSRRBIXFUMOU-JEDNCBNOSA-N
Other Notes
Chiral derivatizing agent for acids (as mixed anhydride) to determine the enantiomer ratio
Regulatory Information
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A conductometric method for the assay of amidase and peptidase activities.
C R Hill et al.
Analytical biochemistry, 120(1), 165-175 (1982-02-01)
[Leucinamide specific cytosol leucine aminopeptidase].
T Kanno
Rinsho byori. The Japanese journal of clinical pathology, 30(5), 502-506 (1982-05-01)
Andrew R Conrad et al.
The journal of physical chemistry. A, 115(34), 9676-9681 (2011-05-12)
Rotational spectra were recorded for two isotopic species of two conformers of the amide derivative of leucine in the range of 10.5-21 GHz and fit to a rigid rotor Hamiltonian. Ab initio calculations at the MP2/6-311++G(d,p) level identified the low
Determination of the enantiomers of ketoprofen in blood plasma by ion-pair extraction and high-performance liquid chromatography of leucinamide derivatives.
S Björkman
Journal of chromatography, 414(2), 465-471 (1987-03-06)
Y L Wang et al.
Solid state nuclear magnetic resonance, 14(1), 19-32 (1999-07-17)
Proton NMR relaxation time measurements were carried out on solid tyrosine derivatives: acetyl-L-tyrosine ethyl ester (Ac-Tyroet), N-carbobenzyloxy-L-tyrosine ethyl ester (CBZ-Tyroet), N-trifluoroacetyl-L-tyrosine ethyl ester (TFAc-Tyroet) and their mixtures with L-leucinamide. It was found that spin-lattice relaxation was driven mainly by methyl
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