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Merck
CN

61915

D-Leucinol

purum, ≥98.0% (sum of enantiomers, GC)

Synonym(s):

(R)-2-Amino-4-methyl-1-pentanol

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About This Item

Empirical Formula (Hill Notation):
C6H15NO
CAS Number:
Molecular Weight:
117.19
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1719241
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grade

purum

assay

≥98.0% (sum of enantiomers, GC)

optical activity

[α]20/D −4.0±0.5°, c = 9% in ethanol

optical purity

enantiomeric ratio: ≥99:1 (GC)

refractive index

n20/D 1.450

density

0.907 g/mL at 20 °C (lit.)

SMILES string

CC(C)C[C@@H](N)CO

Other Notes

N-Protection and transformation of OH group; Selective O-derivatization

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

194.0 °F - closed cup

flash_point_c

90 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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M. Kondo et al.
Chemistry Letters (Jpn), 997-997 (1987)
R.E. TenBrink
The Journal of Organic Chemistry, 52, 418-418 (1987)
J.R. Luly et al.
The Journal of Organic Chemistry, 52, 1487-1487 (1987)
C.F. Stanfield et al.
The Journal of Organic Chemistry, 47, 3016-3016 (1982)
Griet Van Zeebroeck et al.
Nature chemical biology, 5(1), 45-52 (2008-12-09)
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid analogs to identify compounds that act on Gap1

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