61990
Leu-Gly-Gly
≥99.0% (sum of enantiomers, TLC)
Synonym(s):
L-Leucyl-glycyl-glycine
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About This Item
Linear Formula:
(CH3)2CHCH2CH(NH2)CONHCH2CONHCH2COOH
CAS Number:
Molecular Weight:
245.28
Beilstein:
1728928
EC Number:
MDL number:
UNSPSC Code:
12352200
Assay
≥99.0% (sum of enantiomers, TLC)
optical activity
[α]20/D +59±2°, c = 2% in H2O
impurities
≤1% Leu + Gly
mp
~220 °C (dec.)
SMILES string
CC(C)C[C@H](N)C(=O)NCC(=O)NCC(O)=O
InChI
1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
InChI key
VWHGTYCRDRBSFI-ZETCQYMHSA-N
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Amino Acid Sequence
Leu-Gly-Gly
Other Notes
Substrate for the assay of aminopeptidase; and brain aminopeptidase
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E.L. Smith
Methods in Enzymology, 2, 83-83 (1955)
N. Marks et al.
Methods in Enzymology, 19, 534-534 (1970)
M Hayashi et al.
Journal of biochemistry, 87(5), 1403-1411 (1980-05-01)
Aminotripeptidase [EC 3.4.11.4] was purified from monkey brain by a five-step procedure comprising extraction from brain homogenate, ammonium sulfate fractionation, DEAE-cellulose chromatography, hydroxylapatide chromatography, and Sephadex G-200 gel filtration. A purification of 1,100-fold over the homogenate was achieved and the
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