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Merck
CN

62696

Luteolin

≥99.0% (TLC)

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
Molecular Weight:
286.24
EC Number:
207-741-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
292084
MDL number:
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assay

≥99.0% (TLC)

mp

~330 °C (lit.)

storage temp.

2-8°C

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

Gene Information

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Regulatory Information

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Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Chithan Kandaswami et al.
In vivo (Athens, Greece), 19(5), 895-909 (2005-08-16)
The flavonoids are polyphenolic compounds found as integral components of the human diet. They are universally present as constituents of flowering plants, particularly of food plants. The flavonoids are phenyl substituted chromones (benzopyran derivatives) consisting of a 15-carbon basic skeleton
Benguo Liu et al.
Food chemistry, 141(2), 900-906 (2013-06-26)
The formation of supramolecular inclusion complexes between luteolin and five cyclodextrins namely β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), hydroxyethyl-β-cyclodextrin (HE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and glucosyl-β-cyclodextrin (G-β-CD) was investigated. Results from phase-solubility studies showed that luteolin formed 1:1 stoichiometric inclusion complexes with these cyclodextrins
Leticia Correa Manjolin et al.
Food chemistry, 141(3), 2253-2262 (2013-07-23)
Fisetin, quercetin, luteolin and 7,8-hydroxyflavone show high activity in Leishmania cultures and present low toxicity to mammalian cells. In this work, the structural aspects of 13 flavonoids were analyzed for their inhibition of the arginase enzyme from Leishmania (Leishmania) amazonensis.
Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma

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