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Merck
CN

62860

DL-Lysine

purum, ≥95.0% (NT)

Synonym(s):

(±)-2,6-Diaminocaproic acid

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About This Item

Linear Formula:
NH2(CH2)4CH(NH2)COOH
CAS Number:
Molecular Weight:
146.19
EC Number:
200-740-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1616991
MDL number:
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grade

purum

assay

≥95.0% (NT)

impurities

≤2% water

mp

170 °C (dec.) (lit.), ~175 °C

application(s)

peptide synthesis

SMILES string

NCCCCC(N)C(O)=O

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)

InChI key

KDXKERNSBIXSRK-UHFFFAOYSA-N

Regulatory Information

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Da Li et al.
Oncotarget, 5(5), 1315-1325 (2014-03-29)
Phosphatidylethanolamine N-methyltransferase (PEMT) plays a critical role in breast cancer progression. However, the epigenetic mechanism regulating PEMT transcription remains largely unknown. Here, we show that the first promoter-specific transcript 1 is the major PEMT mRNA species, and methylation of the
Hideo Kudo et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(6), 1636-1647 (2014-01-29)
To clarify the role of interleukin-20 (IL-20) in the regulatory mechanism of extracellular matrix expression and to determine the contribution of IL-20 to the phenotype of systemic sclerosis (SSc). Protein and messenger RNA (mRNA) levels of collagen, Fli-1, IL-20, and
Yorito Hattori et al.
Stroke, 45(11), 3403-3411 (2014-09-13)
Silent information regulator 2 homolog 1 (SIRT1) is a protein deacetylase that has been reported to suppress neurodegenerative and cardiovascular diseases in model organisms. We hypothesized that neurovascular protection is one of the diverse actions of SIRT1. This study was
Lisa M Kaminskas et al.
Molecular pharmaceutics, 12(2), 432-443 (2014-12-09)
The current study sought to explore whether the subcutaneous administration of lymph targeted dendrimers, conjugated with a model chemotherapeutic (methotrexate, MTX), was able to enhance anticancer activity against lymph node metastases. The lymphatic pharmacokinetics and antitumor activity of PEGylated polylysine
Chen Zhu et al.
Nature communications, 6, 6072-6072 (2015-01-24)
The inhibitory receptor T-cell immunoglobulin and mucin domain-3 (Tim-3) has emerged as a critical regulator of the T-cell dysfunction that develops in chronic viral infections and cancers. However, little is known regarding the signalling pathways that drive Tim-3 expression. Here

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