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About This Item

Linear Formula:
CH2[P(O)(OCH2CH3)2]2
CAS Number:
Molecular Weight:
288.21
Beilstein:
1813241
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
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grade

purum

Assay

≥97.0% (GC)

reaction suitability

reaction type: C-C Bond Formation

refractive index

n20/D 1.442 (lit.)
n20/D 1.442

bp

171-174 °C/11 mmHg (lit.)

density

1.16 g/mL at 25 °C (lit.)

SMILES string

CCOP(=O)(CP(=O)(OCC)OCC)OCC

InChI

1S/C9H22O6P2/c1-5-12-16(10,13-6-2)9-17(11,14-7-3)15-8-4/h5-9H2,1-4H3

InChI key

STJWVOQLJPNAQL-UHFFFAOYSA-N

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Application

Reactant for synthesis of:
  • Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
  • Unnatural alpha-amino acid derivatives containing gem-biphosphonates
  • Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption
  • Lycopene via Wittig-Horner reaction
  • Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase
  • Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase

Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition

Other Notes

Horner-Wittig reagent for the synthesis of vinylic phosphonates ; Preparation of isosters of phosphates by Horner- Wittig reaction followed by hydrogenation

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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