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Merck
CN

64330

D-Methionine

puriss., ≥99.0% (NT)

Synonym(s):

(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2S
CAS Number:
Molecular Weight:
149.21
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
206-483-6
Beilstein/REAXYS Number:
1722293
MDL number:
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grade

puriss.

assay

≥99.0% (NT)

optical activity

[α]20/D −23.7±0.5°, c = 5% in 5 M HCl

application(s)

peptide synthesis

SMILES string

[Cl-].[N+](CCO)(Cc2c(cccc2)C=C)(C)C.c1(c(cccc1)C=C)C=C, CSCC[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

InChI key

FFEARJCKVFRZRR-SCSAIBSYSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)
Yi-Sin Wong et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(6), e13803-e13803 (2020-01-29)
Cisplatin is a widely used antineoplastic drug. However, cisplatin-induced dyspepsia syndromes, including delayed gastric emptying, gastric distension, early satiety, nausea, and vomiting, often force patients to take doses lower than those prescribed or even refuse treatment. D-methionine has an appetite-enhancing
Calvin Wu et al.
Journal of neural transmission (Vienna, Austria : 1996), 121(7), 683-693 (2014-02-18)
Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated their neuronal modulatory actions. We