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Merck
CN

64330

Sigma-Aldrich

D-Methionine

puriss., ≥99.0% (NT)

Synonym(s):

(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2S
CAS Number:
Molecular Weight:
149.21
Beilstein:
1722293
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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grade

puriss.

Assay

≥99.0% (NT)

optical activity

[α]20/D −23.7±0.5°, c = 5% in 5 M HCl

application(s)

peptide synthesis

SMILES string

[Cl-].[N+](CCO)(Cc2c(cccc2)C=C)(C)C.c1(c(cccc1)C=C)C=C
CSCC[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

InChI key

FFEARJCKVFRZRR-SCSAIBSYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Yi-Sin Wong et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(6), e13803-e13803 (2020-01-29)
Cisplatin is a widely used antineoplastic drug. However, cisplatin-induced dyspepsia syndromes, including delayed gastric emptying, gastric distension, early satiety, nausea, and vomiting, often force patients to take doses lower than those prescribed or even refuse treatment. D-methionine has an appetite-enhancing
Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)
Calvin Wu et al.
Journal of neural transmission (Vienna, Austria : 1996), 121(7), 683-693 (2014-02-18)
Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated their neuronal modulatory actions. We
Olga Z Karicheva et al.
Nucleic acids research, 39(18), 8173-8186 (2011-07-05)
Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m.3243A>G mutation was described
Guo-Lin Chen et al.
Gene, 435(1-2), 53-62 (2009-04-07)
Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5'-UTR in gene expression regulation. This study aimed

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