64330
D-Methionine
puriss., ≥99.0% (NT)
Synonym(s):
(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid
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About This Item
Empirical Formula (Hill Notation):
C5H11NO2S
CAS Number:
Molecular Weight:
149.21
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
206-483-6
Beilstein/REAXYS Number:
1722293
MDL number:
SMILES string
[Cl-].[N+](CCO)(Cc2c(cccc2)C=C)(C)C.c1(c(cccc1)C=C)C=C, CSCC[C@@H](N)C(O)=O
InChI key
FFEARJCKVFRZRR-SCSAIBSYSA-N
InChI
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
grade
puriss.
assay
≥99.0% (NT)
optical activity
[α]20/D −23.7±0.5°, c = 5% in 5 M HCl
application(s)
peptide synthesis
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Yi-Sin Wong et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(6), e13803-e13803 (2020-01-29)
Cisplatin is a widely used antineoplastic drug. However, cisplatin-induced dyspepsia syndromes, including delayed gastric emptying, gastric distension, early satiety, nausea, and vomiting, often force patients to take doses lower than those prescribed or even refuse treatment. D-methionine has an appetite-enhancing
Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)
Calvin Wu et al.
Journal of neural transmission (Vienna, Austria : 1996), 121(7), 683-693 (2014-02-18)
Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated their neuronal modulatory actions. We
Guo-Lin Chen et al.
Gene, 435(1-2), 53-62 (2009-04-07)
Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5'-UTR in gene expression regulation. This study aimed
Olga Z Karicheva et al.
Nucleic acids research, 39(18), 8173-8186 (2011-07-05)
Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m.3243A>G mutation was described
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