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Merck
CN

65825

NG-Methyl-L-arginine acetate salt

≥95% (HPLC)

Synonym(s):

Nω-Methyl-L-arginine acetate salt, L-NMMA, N5-(Methylamidino)-L-ornithine acetate salt, NG-Monomethyl-L-arginine acetate salt

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About This Item

Empirical Formula (Hill Notation):
C7H16N4O2 · C2H4O2
CAS Number:
Molecular Weight:
248.28
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
6674255
MDL number:
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assay

≥95% (HPLC)

impurities

≤3.5% water

solubility

H2O: 1 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O

InChI

1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)/t5-;/m0./s1

InChI key

IKPNWIGTWUZCKM-JEDNCBNOSA-N

Other Notes

Endothelium-derived relaxing factor inhibitor


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Parag R Gajendragadkar et al.
PloS one, 9(6), e99070-e99070 (2014-06-10)
The mechanisms by which a 'Mediterranean diet' reduces cardiovascular disease (CVD) burden remain poorly understood. Lycopene is a potent antioxidant found in such diets with evidence suggesting beneficial effects. We wished to investigate the effects of lycopene on the vasculature
Evidence for cyclooxygenase-dependent sweating in young males during intermittent exercise in the heat.
Naoto Fujii et al.
The Journal of physiology, 592(23), 5327-5339 (2014-10-19)
I Sakuma et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(22), 8664-8667 (1988-11-01)
Nitric oxide (NO) is a major endothelium-derived relaxing factor (EDRF) released in response to vasodilating amines, peptides, proteins, ionophores, and nucleotides. EDRF is an important regulator of smooth muscle tone and platelet aggregation and adhesion. Histamine and acetylcholine relax the