Key Documents

View All Documentation

66681

4,4′-Methylene-bis(2-chloroaniline)

Name: 4,4′-Methylene-bis(2-chloroaniline)
Brand: SIAL

analytical standard

Synonym(s):

2,2′-Dichloro-4,4′-methylenedianiline, 4,4′-Diamino-3,3′-dichlorodiphenylmethane

Select a Size

Change View

About This Item

Linear Formula:

CH₂[C₆H₃(Cl)NH₂]₂

CAS Number:

101-14-4

Molecular Weight:

267.15

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329760302

EC Number:

202-918-9

Beilstein/REAXYS Number:

1882318

MDL number:

MFCD00047829

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

202-214 °C/0.3 mmHg (lit.)

mp

102-107 °C (lit.)

application(s)

environmental

format

neat

SMILES string

Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl

InChI

1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2

InChI key

IBOFVQJTBBUKMU-UHFFFAOYSA-N

Description

General description

4,4′-Methylene-bis(2-chloroaniline) is an azo dye metabolite that is deemed toxic to the environment.

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

4,4′-Methylene-bis(2-chloroaniline) may be used as an analytical reference standard for the determination of 4,4′-methylene-bis(2-chloroaniline) in:

Urine samples by high performance liquid chromatography (HPLC).
Textile samples by HPLC coupled to tandem mass spectrometry (MS/MS) equipped with multiple reaction monitoring (MRM) mode of detection.
Plastic multilayer food packaging materials by LC-Orbitrap-full scan-high resolution mass spectrometry (HRMS) equipped with electrospray ionization (ESI) source.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Standard for determining aromatic amines released from azo-dyes in commodities

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.