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Merck
CN

66746

Dichloromethane

suitable for HPLC, ≥99.8% (GC)

Synonym(s):

Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
EC Number:
200-838-9
UNSPSC Code:
12190000
PubChem Substance ID:
Beilstein/REAXYS Number:
1730800
MDL number:
Assay:
≥99.8% (GC)
Grade:
HPLC grade
Technique(s):
HPLC: suitable
Bp:
39.8-40 °C (lit.)
Vapor pressure:
24.45 psi ( 55 °C), 6.83 psi ( 20 °C)
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InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

InChI

1S/CH2Cl2/c2-1-3/h1H2

SMILES string

ClCCl

grade

HPLC grade

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

assay

≥99.8% (GC)

form

liquid

autoignition temp.

1223 °F

shelf life

limited shelf life, expiry date on the label

contains

~0.0025% amylene as stabilizer

expl. lim.

22 %

technique(s)

HPLC: suitable

impurities

≤0.001% free acid (as HCl), ≤0.02% water

evapn. residue

≤0.001%

transmittance

232 nm, ≥10%, 240 nm, ≥50%, 245 nm, ≥80%, 260 nm, ≤98%

Quality Level

bp

39.8-40 °C (lit.)

solvent strength ε (Al2O3)

0.42 (Lit.)

λ

1 cm path, H2O reference

UV absorption

λ: 232 nm Amax: 1.00, λ: 240 nm Amax: 0.31, λ: 245 nm Amax: 0.10, λ: 260 nm Amax: 0.01

storage temp.

2-8°C

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Other Notes

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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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Shinji Kumagai et al.
Occupational and environmental medicine, 70(7), 508-510 (2013-03-16)
The present study was conducted to investigate the relationship between occupational chemical exposure and incidence of cholangiocarcinoma among workers in the offset colour proof-printing section of a small printing company in Osaka, Japan. We identified 51 men who had worked
K E Mauck et al.
Integrative and comparative biology, 54(2), 193-209 (2014-04-22)
Recent research suggests that plant viruses, and other pathogens, frequently alter host-plant phenotypes in ways that facilitate transmission by arthropod vectors. However, many viruses infect multiple hosts, raising questions about whether these pathogens are capable of inducing transmission-facilitating phenotypes in
Laura Golsteijn et al.
Environment international, 71, 36-45 (2014-06-28)
The present paper describes a method that accounts for variation in indoor chemical exposure settings and accompanying human toxicity in life cycle assessment (LCA). Metal degreasing with dichloromethane was used as a case study to show method in practice. We
Angharad M Roberts et al.
Science translational medicine, 7(270), 270ra6-270ra6 (2015-01-16)
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an abundant structural, sensory, and signaling filament in muscle) as a common cause of end-stage dilated cardiomyopathy (DCM) promises new prospects for improving heart failure management. However, realization
Guilherme Asmar Alencar et al.
The Journal of clinical endocrinology and metabolism, 99(8), E1501-E1509 (2014-04-09)
Primary macronodular adrenal hyperplasia (PMAH) is a rare cause of Cushing's syndrome, usually characterized by functioning adrenal macronodules and increased cortisol production. Familial clustering of PMAH has been described, suggesting an inherited genetic cause for this condition. The aim of

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