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Merck
CN

67126

Oxolinic acid

analytical standard

Synonym(s):

5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C13H11NO5
CAS Number:
Molecular Weight:
261.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
238-750-8
Beilstein/REAXYS Number:
620635
MDL number:
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Product Name

Oxolinic acid, analytical standard

InChI key

KYGZCKSPAKDVKC-UHFFFAOYSA-N

InChI

1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

SMILES string

CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: quinolone

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

农药列管产品
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gyrA and parC associated with quinolone resistance in Vibrio anguillarum.
C Rodkhum et al.
Journal of fish diseases, 31(5), 395-399 (2008-04-11)
Hyeok Ran Kwon et al.
Pest management science, 66(6), 634-639 (2010-02-13)
Pine wilt disease (PWD) is very complex and has been reported to be caused by pine wood nematode, Bursaphelenchus xylophilus (Steiner & Buhrer) Nickle, and its accompanying bacteria. However, there is no report on the control of PWD by antibacterial
Xiuhong Wang et al.
The Journal of antimicrobial chemotherapy, 65(3), 520-524 (2010-01-14)
Quinolone-mediated death of Escherichia coli has been proposed to occur by two pathways. One is blocked by inhibitors of protein synthesis; the other is not. It is currently unknown how these two pathways fit with the recent observation that hydroxyl
Ana L Giraldo et al.
Water research, 44(18), 5158-5167 (2010-07-17)
In the work presented here, a photocatalytic system using titanium Degussa P-25 in suspension was used to evaluate the degradation of 20mg L(-1) of antibiotic oxolinic acid (OA). The effects of catalyst load (0.2-1.5 g L(-1)) and pH (7.5-11) were
Kalliopi C Skyrianou et al.
Journal of inorganic biochemistry, 105(10), 1273-1285 (2011-08-09)
The nickel(II) complexes with the quinolone antibacterial agents oxolinic acid, flumequine, enrofloxacin and sparfloxacin in the presence of the N,N'-donor heterocyclic ligand 2,2'-bipyridylamine have been synthesized and characterized. The quinolones act as bidentate ligands coordinated to Ni(II) ion through the

Articles

LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.

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