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Merck
CN

67805

Idebenone

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C19H30O5
CAS Number:
Molecular Weight:
338.44
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

analytical standard

Quality Level

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChI key

JGPMMRGNQUBGND-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Claudia Carbone et al.
Expert opinion on drug delivery, 9(11), 1377-1392 (2012-10-23)
Idebenone (IDE) is an antioxidant compound, structurally related to coenzyme Q10. Its therapeutic potential is growing in different application areas, as demonstrated by the number of experimental works and patents produced in very recent years. Cyclodextrin inclusion complexes, liposomes, microemulsions
[The use of idebenone (noben) in neurological practice].
I V Damulin
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 106(11), 66-71 (2006-12-21)
Michael H Parkinson et al.
Journal of neurochemistry, 126 Suppl 1, 125-141 (2013-07-24)
Friedreich's ataxia is a debilitating progressive neurodegenerative disease associated with cardiomyopathy and other features. The underlying cause is a deficiency of the mitochondrial protein frataxin which causes mitochondrial iron deposition, increased oxidative stress and impaired adenosine triphosphate production. Over the



Global Trade Item Number

SKUGTIN
67805-10MG04061832748528