69345
Methyl-β-D-thiogalactoside
≥99.0% (HPLC)
Synonym(s):
Methyl-1-thio-β-D-galactopyranoside, TMG
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About This Item
Empirical Formula (Hill Notation):
C7H14O5S
CAS Number:
Molecular Weight:
210.25
PubChem Substance ID:
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
81583
MDL number:
assay
≥99.0% (HPLC)
storage temp.
−20°C
SMILES string
CS[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
InChI
1S/C7H14O5S/c1-13-7-6(11)5(10)4(9)3(2-8)12-7/h3-11H,2H2,1H3/t3-,4+,5+,6-,7+/m1/s1
InChI key
LZFNFLTVAMOOPJ-PZRMXXKTSA-N
Other Notes
Inducer of β-galactosidase
Regulatory Information
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J.B. Gonzalez et al.
Biotechnology Letters, 4, 369-369 (1982)
Anja Marbach et al.
Journal of biotechnology, 157(1), 82-88 (2011-11-15)
Most commonly used expression systems in bacteria are based on the Escherichia coli lac promoter. Furthermore, lac operon elements are used today in systems and synthetic biology. In the majority of the cases the gratuitous inducers IPTG or TMG are
E H Heuberger et al.
European journal of biochemistry, 267(1), 228-234 (1999-12-22)
A carbohydrate-transport assay was developed that does not require isotopically labelled substrates, but allows transport reactions to be followed spectrophotometrically. It makes use of a membrane system (hybrid membranes or proteoliposomes) bearing the transport system of interest, and a pyrroloquinoline
B M Hogema et al.
Molecular microbiology, 28(4), 755-765 (1998-06-27)
The main mechanism causing catabolite repression by glucose and other carbon sources transported by the phosphotransferase system (PTS) in Escherichia coli involves dephosphorylation of enzyme IIA(Glc) as a result of transport and phosphorylation of PTS carbohydrates. Dephosphorylation of enzyme IIA(Glc)
Parameters affecting the use of the lac repressor system in eukaryotic cells and transgenic animals.
D L Wyborski et al.
Environmental and molecular mutagenesis, 28(4), 447-458 (1996-01-01)
Elements of the lactose operon were used to study parameters affecting gene expression in cultured cells and transgenic animals. A Lac repressor protein containing a nuclear transport signal was shown to inhibit expression of a reporter gene by interacting with
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