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Merck
CN

69577

α-Methyl-DL-tyrosine

≥95% (NT)

Synonym(s):

DL-2-Methyl-3-(4-hydroxyphenyl)alanine, AMPT

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About This Item

Linear Formula:
4-(HO)C6H4CH2C(CH3)(NH2)CO2H
CAS Number:
Molecular Weight:
195.22
EC Number:
211-523-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2938704
MDL number:
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assay

≥95% (NT)

form

powder

ign. residue

≤0.05%

mp

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(N)(Cc1ccc(O)cc1)C(O)=O

InChI

1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)

InChI key

NHTGHBARYWONDQ-UHFFFAOYSA-N

Other Notes

Inhibitor (Ki 5 uM) of tyrosine hydroxylase


Regulatory Information

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Tyrosine hydroxylase inhibitors.
K E Moore et al.
Federation proceedings, 30(3), 859-870 (1971-05-01)
Kinuyo Iwata et al.
The Journal of reproduction and development, 57(3), 379-384 (2011-03-02)
Ketosis is found in various pathophysiological conditions, including diabetes and starvation, that are accompanied by suppression of gonadal activity. The aim of the present study was to determine the role of ketone body in the brain in regulating pulsatile luteinizing
Ewa Bromek et al.
Journal of neurochemistry, 118(5), 806-815 (2011-06-10)
The cytochrome P450-mediated synthesis of dopamine from tyramine has been shown in vitro. The aim of the present study was to demonstrate the ability of rat cytochrome P450 (CYP) 2D to synthesize dopamine from tyramine in the brain in vivo.