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Merck
CN

69600

4-Methylumbelliferyl β-D-glucopyranoside

suitable for fluorescence, ≥99.0% (HPLC)

Synonym(s):

MUD

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About This Item

Empirical Formula (Hill Notation):
C16H18O8
CAS Number:
18997-57-4
Molecular Weight:
338.31
EC Number:
242-736-7
UNSPSC Code:
12352204
PubChem Substance ID:
24885955
Beilstein/REAXYS Number:
94672
MDL number:
MFCD00063694

Key Documents

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assay

≥99.0% (HPLC)

optical activity

[α]20/D −99±4°, c = 0.3% in H2O

mp

210-212 °C

fluorescence

λex 365 nm; λem 445 nm in 0.1 M sodium acetate pH 5.0 (after cleavage by β-glucosidase)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1

InChI key

YUDPTGPSBJVHCN-YMILTQATSA-N

Other Notes

Substrate for β-glucosidase

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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L B Daniels et al.
The Journal of biological chemistry, 256(24), 13004-13013 (1981-12-25)
A cytoplasmic beta-glucosidase has been isolated and purified 9,000-fold to homogeneity from the liver of a case of type 1 Gaucher's disease to a specific activity of 400,000 nmol/h/mg of protein. Although markedly elevated above control levels in this case
V Bachanova et al.
Bone marrow transplantation, 50(2), 197-203 (2014-11-18)
Alternative donor transplantation is increasingly used for high-risk lymphoma patients. We analyzed 1593 transplant recipients (2000-2010) and compared transplant outcomes in recipients of 8/8 allele HLA-A, -B, -C and DRB1 matched unrelated donors (MUDs; n=1176), 7/8 allele HLA mismatched unrelated
Nao Yamakawa et al.
Biochimie, 89(11), 1396-1408 (2007-05-29)
Sulfated sialic acid (SiaS) is a unique sialic acid (Sia) derivative in which an additional anionic group is attached to a carboxylated monosaccharide. Very little is known about the occurrence and biologic function of SiaS, due to the limitations of
Pasi Huttunen et al.
Pediatric blood & cancer, 62(3), 522-528 (2014-11-25)
Increasing evidence suggests that early and rapid lymphocyte recovery following allogeneic hematopoietic stem cell transplantation (HSCT) is associated with better survival. We retrospectively analyzed very early lymphocyte subset counts following transplantation from our 5-year pediatric allogeneic HSCT material to find
H Nakasone et al.
Bone marrow transplantation, 50(4), 559-565 (2014-12-23)
The impact of the conditioning intensity and TBI on acute GVHD (aGVHD) is still a matter of debate. We analyzed 6848 adult recipients who received allogeneic hematopoietic cell transplants (HCT) between 2006 and 2011 in Japan. The subjects were divided
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