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Merck
CN

69732

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

Synonym(s):

Lithium mupirocin solution, Li-MUP, MUP supplement

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About This Item

Empirical Formula (Hill Notation):
C26H43LiO9
CAS Number:
73346-79-9
Molecular Weight:
506.56
NACRES:
NA.85
PubChem Substance ID:
329761909
UNSPSC Code:
41171614
MDL number:
MFCD11977847

Key Documents

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Product Name

Lithium mupirocin Supplement, suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

agency

ISO 29981:2010

sterility

sterile (Filtered and Aseptic Handled)
sterile

form

liquid

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

Quality Level

100

Related Categories

Application

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

General description

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Other Notes

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4587
BCCJ9097
BCCH6039
BCCH0638
BCCG6315

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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
M Lepainteur et al.
The Journal of hospital infection, 83(4), 333-336 (2013-02-19)
In neonatal intensive care units, topical agents represent an increasing part of the infection control armamentarium. Fifty-one coagulase-negative staphylococci (CNS) isolated from catheter-associated bloodstream infections in very preterm neonates were investigated in this study: 41.2% exhibited decreased susceptibility to at
Sapna Mehta et al.
Clinical orthopaedics and related research, 471(7), 2367-2371 (2013-02-21)
Hospital-acquired infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a source of morbidity and mortality. S. aureus is the most common pathogen in prosthetic joint infections and the incidence of MRSA is increasing. The purposes of this study were (1)
Staph aureus has long been recognized as being more prevalent in cultures from patients with chronic rhinosinusitis(CRS) compared to those with acute rhinosinusitis.
Peter H Hwang
International forum of allergy & rhinology, 3(2), 81-82 (2013-02-16)
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