69761
(±)-Mevalonolactone
purum, ≥96.0% (T)
Synonym(s):
(±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, DL-Mevalolactone, DL-Mevalonic acid lactone
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About This Item
Empirical Formula (Hill Notation):
C6H10O3
CAS Number:
Molecular Weight:
130.14
EC Number:
211-615-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
80960
MDL number:
InChI key
JYVXNLLUYHCIIH-UHFFFAOYSA-N
InChI
1S/C6H10O3/c1-6(8)2-3-9-5(7)4-6/h8H,2-4H2,1H3
SMILES string
CC1(O)CCOC(=O)C1
grade
purum
assay
≥96.0% (T)
impurities
salt, none detected
mp
24-27 °C
storage temp.
2-8°C
Other Notes
Lactone of mevalonic acid which is a very important connecting link in the biosynthesis of isoprenoids
Disclaimer
can form fused mass at low temperatures
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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The biosynthesis of cholesterol.
G POPJAK et al.
Advances in enzymology and related subjects of biochemistry, 22, 281-335 (1960-01-01)
B. Preiss, ed.
Regulation of HMG-CoA Reductase null
R. Clayton
Quart. Rev., 19, 168-168 (1965)
J.W. Porter et al.
Biosynthesis of Isoprenoid Compounds, vol. 1 and 2 null
Monica P Polo et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 84(1), 102-111 (2006-02-08)
Monoterpenes have multiple pharmacological effects on the metabolism of mevalonate. Geraniol, a dietary monoterpene, has in vitro and in vivo anti-tumor activity against several cell lines. We have studied the effects of geraniol on growth, fatty-acid metabolism, and mevalonate metabolism
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