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Merck
CN

70450

Sigma-Aldrich

2-Naphthol

≥99.0%

Synonym(s):

β-Naphthol, 2-Hydroxynaphthalene

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About This Item

Linear Formula:
C10H7OH
CAS Number:
Molecular Weight:
144.17
Beilstein:
742134
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
MA.02
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vapor density

4.97 (vs air)

Quality Level

vapor pressure

10 mmHg ( 145.5 °C)

Assay

≥99.0% (GC)
≥99.0%

form

solid

impurities

≤0.5% 1-naphthol

ign. residue

≤0.05%

bp

285-286 °C (lit.)

mp

120-122 °C (lit.)
121-122 °C

fluorescence

λex 320 nm; λem 410 nm in 0.1 M NaOH

SMILES string

Oc1ccc2ccccc2c1

InChI

1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H

InChI key

JWAZRIHNYRIHIV-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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General description

2-Naphthol (2OH) is a hydroxyarene molecule, which when electronically excited forms strong acid. Excited 2OH dissociates only in water. It has a slight phenolic odor. It is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. It is one of the most commonly used fluorescence dye.

Application

2OH has been used as a fluorescence indicator which changes fluorescence intensity at varied temperatures when embedded in aqueous Poly(vinly alcohol)/borax gel networks.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

307.4 °F - closed cup

Flash Point(C)

153 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Armour, Margaret-Ann
Hazardous Laboratory Chemicals Disposal Guide, 325-325 (2003)
Solvatochromism of ?-Naphthol
Solntsev, Kyril M., Dan Huppert, and Noam Agmon
The Journal of Physical Chemistry A, 102.47, 9599-9606 (1998)
A novel fluorescence temperature sensor based on a surfactant-free PVA/borax/2-naphthol hydrogel network system.
Lee, Sang Min, et al.
Journal of Applied Polymer Science, 93.5, 2114-2118 (2004)
L E King et al.
Environmental science & technology, 48(19), 11637-11645 (2014-08-26)
Hamilton Harbour, Ontario, Canada is one of the most polluted sites on the Great Lakes, and is subject to substantial airborne pollution due to emissions from both heavy industry and intense vehicle traffic. Mutagenic Polycyclic aromatic hydrocarbons (PAHs) are present
Glenn Talaska et al.
Toxicology letters, 213(1), 45-48 (2011-05-26)
Urinary bladder cancer is a historical disease of rubber workers often been associated with exposure to aromatic amines such as 2-naphthylamine. While exposure to these compounds has decreased markedly over time, the bladder cancer risk has not decreased in direct

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