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Merck
CN

71090

1-Naphthyl phosphate monosodium salt monohydrate

≥98.0% (HPLC)

Synonym(s):

α-Naphthyl phosphate monosodium salt monohydrate, Sodium 1-naphthyl phosphate monohydrate

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About This Item

Linear Formula:
C10H7OP(O)(OH)(ONa) · H2O
CAS Number:
Molecular Weight:
264.15
PubChem Substance ID:
UNSPSC Code:
12352202
Beilstein/REAXYS Number:
1877764
MDL number:
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assay

≥98.0% (HPLC)

impurities

≤0.1% free naphthol

solubility

H2O: 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[Na+].[H]O[H].OP([O-])(=O)Oc1cccc2ccccc12

InChI

1S/C10H9O4P.Na.H2O/c11-15(12,13)14-10-7-3-5-8-4-1-2-6-9(8)10;;/h1-7H,(H2,11,12,13);;1H2/q;+1;/p-1

InChI key

NSWUDGODQXQNON-UHFFFAOYSA-M

Application

Preferred substrate for bioanalytical determinations of acid phosphatases, such as prostatic acid phosphatase.
Substrate for phosphatases. Has been used in a continuous assay for acid phosphatase.

Biochem/physiol Actions

Non-specific phosphatase inhibitor. Inhibits acid, alkaline and protein phosphatases.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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E Luchter-Wasylewska
Acta biochimica Polonica, 44(4), 853-859 (1997-01-01)
The described continuous acid phosphatase assay is based on kinetics of the release of 1-naphthol in the course of the enzyme-catalyzed hydrolysis of 1-naphthyl phosphate, measured at 320 nm in aqueous solution and at 322 nm in sodium-bis(2-ethylhexyl)sulfosuccinate isooctane-water reverse
Mukesh K Jaiswal et al.
Journal of leukocyte biology, 96(2), 337-347 (2014-03-14)
a2V is required for maturation of sperm. The decreased expression of a2V at the feto-maternal interphase causes poor pregnancy outcome. The present study examined the role of a2V in spermatogenesis and inflammatory network in the testis. A single dose of
Ángel E Mercado-Pagán et al.
Journal of biomaterials applications, 29(4), 557-565 (2014-06-11)
One of the main challenges for clinical implementation of small diameter vascular grafts (SDVGs) is their limited hemocompatibility. Important design specifications for such grafts include features that minimize the long-term risks of restenosis, fouling, and thrombus formation. In our lab
Xinli Huang et al.
International journal of clinical and experimental pathology, 7(8), 4755-4764 (2014-09-10)
Human liver ischemia/reperfusion injury (IRI) is a common and major clinical problem complicating liver surgery and transplantation. The pathogenesis underlying IRI is complex, involving a series of signaling mediators and mechanisms. This study aimed to investigate the effects of Magnesium
Chang Hoon Moon et al.
Investigational new drugs, 32(3), 400-411 (2013-11-10)
CKD-516 is a benzophenone analog in which the B ring is modified by replacement with a carbonyl group. The study assessed CKD-516 as a vascular disrupting agent or anti-cancer drug. To assess the effect of S516 on vascularization, we analyzed

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