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Merck
CN

71180

Sodium acetate

puriss. p.a., ACS reagent, anhydrous, ≥99.0% (NT)

Synonym(s):

Acetic acid sodium salt

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About This Item

Linear Formula:
CH3COONa
CAS Number:
127-09-3
Molecular Weight:
82.03
EC Number:
204-823-8
UNSPSC Code:
12352300
eCl@ss:
39021906
Beilstein/REAXYS Number:
3595639
MDL number:
MFCD00012459

Key Documents

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InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

SMILES string

[Na+].CC([O-])=O

grade

ACS reagent, puriss. p.a.

assay

≥99.0% (NT)

form

solid

autoignition temp.

1112 °F

loss

≤1% loss on drying, 130 °C

pH

7.0-9.2 (25 °C, 50 mg/mL in H2O)

mp

>300 °C (dec.) (lit.)

solubility

ethanol: soluble(lit.), water: soluble(lit.)

anion traces

chloride (Cl-): ≤20 mg/kg, phosphate (PO43-): ≤5 mg/kg, sulfate (SO42-): ≤20 mg/kg

cation traces

Al: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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General description

Sodium acetate is a colorless compound and its crystals belong to the monoclinic crystal system. Sodium acetate trihydrate can be obtained from the crystallization of sodium acetate in water. Its trihydrate loses water of crystallization on heating at 75°C, while on heating above 120°C, anhydrous sodium acetate is obtained. It can be synthesized by reacting sodium carbonate or sodium hydroxide with acetic acid. It is widely employed in the organic laboratory for the preparation of buffer solutions. It has been reported to inhibit the growth of Listeria monocytogenes.

Application

Sodium acetate may be used in the following studies:
  • Separation and quantification of tartrazine (E 102), amaranth (E 123), erythrosine (E 127) and indigotine (E 132) in soft drinks by reverse phase HPLC method.
  • Preparation of guanidine solution required for the total RNA preparation.
  • Enantiomeric enrichment of (2S)-2-methyl-2-(2-propen-1-yl)-cyclohexanone.

Other Notes

This product has been replaced by 32319-Sigma-Aldrich | Sodium acetate, puriss. p.a., ACS reagent, reag. Ph. Eur., anhydrous | CH3COONa

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBH2345V
BCBH2344V
BCBG3271V
BCBD5126V
BCBD3774V

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PREPARATION OF (S)-2-Allyl-2-methylcyclohexanone (Cyclohexanone, 2-methyl-2-(2-propen-1-yl)-, (2S)-).
Justin T Mohr et al.
Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals, 86, 194-211 (2009-01-01)
The liquid-chromatographic quantification of some synthetic colorants in soft drinks.
Trandafir I, et al.
Scientific Study and Research, 10(1), 73-82 (2009)
Listeria monocytogenes inhibition in refrigerated vacuum packaged turkey bologna by chemical additives.
Wederquist HJ, et al.
Journal of Food Science, 59(3), 498-500 (1994)
R E Kingston et al.
Current protocols in molecular biology, Chapter 4, Unit4-Unit4 (2008-02-12)
Three different methods for RNA preparation using guanidine are presented in this unit--a single-step isolation method employing liquid-phase separation to selectively extract total RNA from tissues and cultured cells and two methods that rely on a CsCl step gradient to
Mari Endo et al.
Journal of gastroenterology, 49(6), 1026-1039 (2013-07-13)
Daikenchuto (DKT), a gastrointestinal prokinetic Japanese herbal medicine, is prescribed for patients with postoperative ileus (POI) and adhesive bowel obstruction following abdominal surgery. Several mechanisms for the amelioration of POI by DKT have been suggested; however, it has remained unclear
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