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Merck
CN

71627

Sodium bicarbonate

BioUltra, ≥99.5% (T)

Synonym(s):

Sodium hydrogen carbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
EC Number:
205-633-8
UNSPSC Code:
12161700
MDL number:
Beilstein/REAXYS Number:
4153970
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product line

BioUltra

assay

≥99.5% (T)

impurities

insoluble matter, passes filter test, ≤0.005% iod red. matter (as I)

pH

7.5-8.5 (25 °C, 1 M in H2O, freshly prepared)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

H2O: 1 M at 20 °C, clear, colorless

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤20 mg/kg, phosphate (PO43-): ≤10 mg/kg, sulfate (SO42-): ≤30 mg/kg

cation traces

Al: ≤10 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤100 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤50 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, NH4+: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: ≤0.01, λ: 280 nm Amax: ≤0.01

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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Other Notes

Important component of perfusion fluid, e.g. Ringer solution

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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H. Sies
Methods in Enzymology, 52, 50-50 (1978)
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This

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