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Merck
CN

71745

Sodium ionophore IV

Selectophore, function tested

Synonym(s):

2,3:11,12-Didecalino-16-crown-5, 2,6,13,16,19-Pentaoxapentacyclo[18.4.4.47,12.01,20.07,12]dotriacontane, DD-16-C-5

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About This Item

Empirical Formula (Hill Notation):
C27H46O5
CAS Number:
Molecular Weight:
450.65
NACRES:
NB.61
PubChem Substance ID:
UNSPSC Code:
26111700
MDL number:
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Product Name

Sodium ionophore IV, Selectophore, function tested

InChI

1S/C27H46O5/c1-5-14-26-15-6-2-11-24(26,10-1)29-18-9-19-30-25-12-3-7-16-27(25,17-8-4-13-25)32-23-21-28-20-22-31-26/h1-23H2/t24-,25-,26+,27+

SMILES string

C1COC23CCCCC2(CCCC3)OCCOCCOC45CCCCC4(CCCC5)OC1

InChI key

ISSCXMQDZJDLSO-PVCJUVKBSA-N

description

for ion-selective electrodes

product line

Selectophore

form

powder

quality

function tested

storage temp.

2-8°C

Quality Level

Application

Selected application examples

General description

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Other Notes

Sodium ionophore which shows an extremely high selectivity for Na over K (1000:1)

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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K Suzuki et al.
Analytical chemistry, 68(1), 208-215 (1996-01-01)
To develop an ionophore that is highly selective for sodium for use in an ion-selective electrode, we propose a model based on 16-crown-5 which has a cavity just the size of Na(+ )and has a "block" subunit to prevent complex
Vedrana Mikušević et al.
The Journal of general physiology, 151(12), 1357-1368 (2019-10-19)
KtrAB is a key player in bacterial K+ uptake required for K+ homeostasis and osmoadaptation. The system is unique in structure and function. It consists of the K+-translocating channel subunit KtrB, which forms a dimer in the membrane, and the
Judith A Heiny et al.
The Journal of general physiology, 151(9), 1146-1155 (2019-07-20)
Ion movements across biological membranes, driven by electrochemical gradients or active transport mechanisms, control essential cell functions. Membrane ion movements can manifest as electrogenic currents or electroneutral fluxes, and either process can alter the extracellular and/or intracellular concentration of the

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