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72490

Ninhydrin

ACS reagent, ≥98.0% (UV)

Synonym(s):

1,2,3-Indantrione monohydrate, 2,2-Dihydroxy-1,3-indanedione, Trioxohydrindene monohydrate

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About This Item

Empirical Formula (Hill Notation):
C9H6O4
CAS Number:
485-47-2
Molecular Weight:
178.14
EC Number:
207-618-1
UNSPSC Code:
12352209
PubChem Substance ID:
329764112
Beilstein/REAXYS Number:
1910963
MDL number:
MFCD00003791
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grade

ACS reagent

assay

≥98.0% (UV)

ign. residue

≤0.1% (as SO4)

mp

250 °C (dec.) (lit.)

SMILES string

OC1(O)C(=O)c2ccccc2C1=O

InChI

1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H

InChI key

FEMOMIGRRWSMCU-UHFFFAOYSA-N

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Application

Used for the detection of free amino groups in amino acids, peptides and proteins.
suitable for Kaiser test

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT2499
BCBS7408V
BCBS1472V
BCBQ8844V

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James Madden et al.
Bioorganic & medicinal chemistry letters, 20(17), 5329-5333 (2010-07-27)
A novel series of 2-aminobenzimidazole inhibitors of BACE1 has been discovered using fragment-based drug discovery (FBDD) techniques. The rapid optimization of these inhibitors using structure-guided medicinal chemistry is discussed.
Chao Li et al.
Journal of biomaterials science. Polymer edition, 23(1-4), 405-424 (2011-02-12)
Biomaterials have been playing important roles in cartilage regeneration. Although many scaffolds have been reported to enhance cartilage regeneration, none of the scaffolds available are optimal regarding mechanical properties, integration with host cartilage and providing proper micro-environment for chondrocyte attachment
Mohd Akram et al.
Colloids and surfaces. B, Biointerfaces, 94, 220-225 (2012-03-01)
The interaction of nickel dipeptide complex [Ni(II)-Gly-Tyr](+) with ninhydrin has been investigated in the absence and presence of cationic cetyltrimethylammonium bromide (CTAB) and gemini (16-s-16, s=4, 5, 6) surfactants spectrophotometrically at 80°C and pH 5.0. The product formed was the
Darren B Hansen et al.
Chemical Society reviews, 34(5), 408-417 (2005-04-27)
Following its discovery by Siegfried Ruhemann in 1910, ninhydrin rapidly became a practical analytical tool. In 1954 it was found to be an important reagent to develop fingerprints on porous surfaces. Since its use in forensic chemistry, many efforts have
Danique van Vliet et al.
Molecular genetics and metabolism, 114(1), 29-33 (2014-12-04)
In phenylketonuria (PKU), cerebral neurotransmitter deficiencies have been suggested to contribute to brain dysfunction. Present treatment aims to reduce blood phenylalanine concentrations by a phenylalanine-restricted diet, while in some patients blood phenylalanine concentrations also respond to cofactor treatment with tetrahydrobiopterin
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