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Merck
CN

72490

Sigma-Aldrich

Ninhydrin

ACS reagent, ≥98.0% (UV)

Synonym(s):

1,2,3-Indantrione monohydrate, 2,2-Dihydroxy-1,3-indanedione, Trioxohydrindene monohydrate

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About This Item

Empirical Formula (Hill Notation):
C9H6O4
CAS Number:
Molecular Weight:
178.14
Beilstein:
1910963
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
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grade

ACS reagent

Assay

≥98.0% (UV)

ign. residue

≤0.1% (as SO4)

mp

250 °C (dec.) (lit.)

SMILES string

OC1(O)C(=O)c2ccccc2C1=O

InChI

1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H

InChI key

FEMOMIGRRWSMCU-UHFFFAOYSA-N

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Application

Used for the detection of free amino groups in amino acids, peptides and proteins.
suitable for Kaiser test

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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James Madden et al.
Bioorganic & medicinal chemistry letters, 20(17), 5329-5333 (2010-07-27)
A novel series of 2-aminobenzimidazole inhibitors of BACE1 has been discovered using fragment-based drug discovery (FBDD) techniques. The rapid optimization of these inhibitors using structure-guided medicinal chemistry is discussed.
Yu-Feng Xie et al.
Journal of neurochemistry, 122(3), 605-618 (2012-05-23)
Neurons located in the trigeminal subnucleus caudalis (Vc) play crucial roles in pain and sensorimotor functions in the orofacial region. Because of many anatomical and functional similarities with the spinal dorsal horn (SDH), Vc has been termed the medullary dorsal
Joseph Almog et al.
Journal of forensic sciences, 56 Suppl 1, S162-S165 (2011-01-14)
We explored the quality distribution of ninhydrin-developed prints on A4 bond paper in two groups of individuals, in Israel and in India. While the quality distributions of the developed marks in both countries had some dissimilarities, both groups showed the
Mendel Friedman
Journal of agricultural and food chemistry, 52(3), 385-406 (2004-02-05)
The reaction of ninhydrin with primary amino groups to form the purple dye now called Ruhemann's purple (RP) was discovered by Siegfried Ruhemann in 1910. In addition, imines such as pipecolic acid and proline, the guanidino group of arginine, the
Mohd Akram et al.
Colloids and surfaces. B, Biointerfaces, 94, 220-225 (2012-03-01)
The interaction of nickel dipeptide complex [Ni(II)-Gly-Tyr](+) with ninhydrin has been investigated in the absence and presence of cationic cetyltrimethylammonium bromide (CTAB) and gemini (16-s-16, s=4, 5, 6) surfactants spectrophotometrically at 80°C and pH 5.0. The product formed was the

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