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Merck
CN

73210

Supelco

4-(4-Nitrobenzyl)pyridine

for spectrophotometric det. of phosphorus-containing pesticides

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About This Item

Empirical Formula (Hill Notation):
C12H10N2O2
CAS Number:
Molecular Weight:
214.22
Beilstein:
170877
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
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Assay

≥98.0% (NT)

Quality Level

form

crystals

quality

for spectrophotometric det. of phosphorus-containing pesticides

technique(s)

thin layer chromatography (TLC): suitable

ign. residue

≤0.1%

mp

69-71 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(Cc2ccncc2)cc1

InChI

1S/C12H10N2O2/c15-14(16)12-3-1-10(2-4-12)9-11-5-7-13-8-6-11/h1-8H,9H2

InChI key

MNHKUCBXXMFQDM-UHFFFAOYSA-N

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Application

for the detection of epoxides and methylating reagents; for spectrophotometric determination of phosphorus-containing pesticides

Other Notes

Reagent for the determination of alkylating agents

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Studies on chemical carcinogens. XXIII. A simple method for characterization of the alkylating ability of compounds by using 4-(p-nitrobenzyl)-pyridine.
Y Kawazoe et al.
Chemical & pharmaceutical bulletin, 30(6), 2077-2086 (1982-06-01)
G.W. Fischer
Analytica Chimica Acta, 92, 149-149 (1977)
P G Penketh et al.
Journal of medicinal chemistry, 37(18), 2912-2917 (1994-09-02)
1,2-Bis(sulfonyl)-1-alkylhydrazines are highly active experimental antineoplastic agents which decompose with first-order kinetics in neutral aqueous solutions. These agents generate approximately 2 mol of the corresponding sulfinate, 1 mol of nitrogen, and 1 mol of the appropriate alcohol, produced as a
Spectrophotometric determination of organophosphorus pesticides with 4-(4-nitrobenzyl)pyridine.
C R Turner
The Analyst, 99(180), 431-434 (1974-07-01)
H B Jiang et al.
Biochemical pharmacology, 60(4), 571-579 (2000-06-30)
Mitomycin C (MC) requires bioreduction prior to the generation of alkylating moieties. NADPH-cytochrome P450 reductase is predominant in metabolic activation of MC in hypoxic cancer cells. In this study, neuronal nitric oxide synthase (nNOS), whose reductase domain is structurally similar

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